Global Patent Index - EP 2633075 A1

EP 2633075 A1 2013-09-04 - CAPTURE OF METHYLATED RNA AND/OR DNA SEQUENCES BY SPECIFIC PROBES

Title (en)

CAPTURE OF METHYLATED RNA AND/OR DNA SEQUENCES BY SPECIFIC PROBES

Title (de)

ERFASSUNG VON METHYLIERTEN RNA- UND/ODER DNA-SEQUENZEN ANHAND SPEZIFISCHER SONDEN

Title (fr)

CAPTURE DE SÉQUENCES D'ARN ET/OU D'ADN MÉTHYLÉ(S) PAR DES SONDES SPÉCIFIQUES

Publication

EP 2633075 A1 (EN)

Application

EP 11784930 A

Priority

  • US 40719110 P
  • DK PA201070456 A
  • DK 2011000121 W

Abstract (en)

[origin: WO2012055409A1] The present invention relates to a technology for specific capture of methylated target DNA and/or RNA by a complementary probe comprising one or more intercalator molecules. The method further involves removal of cytosine residues which are not methylated from the target DNA and/or RNA prior to interaction with the complementary probe. This results in generation of one or more abasic sites which can interact with and/or into where the intercalator molecule can be inserted.

IPC 8 full level (invention and additional information)

C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6827 (2013.01)

Combination set (CPC)

  1. C12Q 1/6827 + C12Q 2525/119 + C12Q 2523/125 + C12Q 2521/531
  2. C12Q 1/6827 + C12Q 2563/173 + C12Q 2523/125 + C12Q 2521/531

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

EPO simple patent family

WO 2012055409 A1 20120503; EP 2633075 A1 20130904

INPADOC legal status


2015-03-04 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20141004

2014-04-23 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20140324

2014-02-05 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) DELETED

2013-09-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20130527

2013-09-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR