EP 2635107 A1 20130911 - PAPAVER BRACTEATUM WITH MODIFIED ALKALOID CONTENT
Title (en)
PAPAVER BRACTEATUM WITH MODIFIED ALKALOID CONTENT
Title (de)
ARMENISCHER MOHN MIT MODIFIZIERTEM ALKALOIDGEHALT
Title (fr)
PAPAVER BRACTEATUM À TENEUR EN ALCALOÏDES MODIFIÉE
Publication
Application
Priority
- AU 2010904872 A 20101101
- AU 2011001400 W 20111031
Abstract (en)
[origin: WO2012058714A1] The present invention relates to genetically modified plants of the species Papaver bracteatum wherein the type or amount of one or more alkaloids produced by the plants has been modified. Specifically, the genetically modified plants have an increased expression of one or more of thebaine 6-O-demethylase, codeine O- demethylase and/or codeinone reductase relative to wild type P. bracteatum such that the genetically modified poppy plants produce an increased quantity of an alkaloid selected from codeine, oripavine and/or morphine relative to a wild type P. bracteatum. Also provided are progeny plants having the genetically modified poppy plants described above as a parent; mutant or derivative plants of the aforementioned plants; reproductive material derived from, straw produced from, straw concentrate produced from, latex derived from, or one or more isolated cells derived from, the aforementioned plants. Methods for producing an alkaloid from the aforementioned plants are also provided, together with nucleic acid and amino acid sequence variants of the 6-O-demethylase and codeine O-demethylase genes.
IPC 8 full level
A01H 5/08 (2006.01); A01H 5/10 (2006.01); C07D 221/28 (2006.01); C07D 489/02 (2006.01); C12N 15/53 (2006.01)
CPC (source: EP)
C07D 489/02 (2013.01); C12N 9/0004 (2013.01); C12N 9/0006 (2013.01); C12N 9/0071 (2013.01); C12N 15/8243 (2013.01); C12P 17/18 (2013.01); C12Y 101/01247 (2013.01); C12Y 114/11031 (2013.01); C12Y 114/11032 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012058714 A1 20120510; EP 2635107 A1 20130911; EP 2635107 A4 20140423
DOCDB simple family (application)
AU 2011001400 W 20111031; EP 11837323 A 20111031