EP 2637644 A1 20130918 - LISURIDE, TERGURIDE AND DERIVATIVES THEREOF FOR USE IN THE PROPHYLAXIS AND/OR TREATMENT OF FIBROTIC CHANGES
Title (en)
LISURIDE, TERGURIDE AND DERIVATIVES THEREOF FOR USE IN THE PROPHYLAXIS AND/OR TREATMENT OF FIBROTIC CHANGES
Title (de)
LISURID, TERGURID UND DERIVATE DAVON ZUR VERWENDUNG IN DER PROPHYLAXE UND/ODER THERAPIE FIBROTISCHER VERÄNDERUNGEN
Title (fr)
LISURIDE, TERGURIDE ET LEURS DÉRIVÉS POUR UNE UTILISATION DANS LA PROPHYLAXIE ET/OU LA THÉRAPIE DE MODIFICATIONS FIBREUSES
Publication
Application
Priority
- EP 11075179 A 20110727
- DE 102010051391 A 20101111
- EP 2011069480 W 20111104
- EP 11781511 A 20111104
Abstract (en)
[origin: WO2012062676A1] The present invention relates to the use of 5-HT2 receptor antagonists and in particular of 8-a-ergolines such as lisuride, terguride and the derivatives thereof as 5-HT2B and 5-HT2A receptor antagonists and antioxidants in preferably higher-dosed and preferably continuous use for the treatment, progression prophylaxis and general prophylaxis of organ fibroses and other pathological organ remodeling caused by mesenchymal proliferation.
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 9/70 (2006.01); A61K 31/48 (2006.01); A61P 9/12 (2006.01)
CPC (source: EP US)
A61K 9/0019 (2013.01 - EP US); A61K 9/0024 (2013.01 - EP US); A61K 9/19 (2013.01 - EP US); A61K 9/7061 (2013.01 - EP US); A61K 31/437 (2013.01 - EP US); A61K 31/48 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 9/12 (2017.12 - EP); A61P 19/04 (2017.12 - EP); C07D 457/12 (2013.01 - EP US)
Citation (search report)
See references of WO 2012062676A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012062676 A1 20120518; AU 2011328299 A1 20130704; BR 112013011640 A2 20171010; CA 2834882 A1 20120518; CA 2834882 C 20180327; CN 103476402 A 20131225; EP 2637644 A1 20130918; JP 2014501710 A 20140123; RU 2013126522 A 20141220; US 2014058108 A1 20140227; US 2015072939 A1 20150312
DOCDB simple family (application)
EP 2011069480 W 20111104; AU 2011328299 A 20111104; BR 112013011640 A 20111104; CA 2834882 A 20111104; CN 201180064644 A 20111104; EP 11781511 A 20111104; JP 2013538137 A 20111104; RU 2013126522 A 20111104; US 201113885058 A 20111104; US 201414492766 A 20140922