Global Patent Index - EP 2641086 B1

EP 2641086 B1 20170104 - METHOD FOR SCREENING DRUGS FOR SUPPRESSING INFLAMMASOME ACTIVITY

Title (en)

METHOD FOR SCREENING DRUGS FOR SUPPRESSING INFLAMMASOME ACTIVITY

Title (de)

VERFAHREN FÜR WIRKSTOFF-SCREENING ZUR UNTERDRÜCKUNG DER INFLAMMASOM-AKTIVITÄT

Title (fr)

MÉTHODE DE CRIBLAGE DE MÉDICAMENTS POUR SUPPRIMER L'ACTIVITÉ DE L'INFLAMMASOME

Publication

EP 2641086 B1 20170104 (EN)

Application

EP 11842110 A 20111117

Priority

  • US 41510210 P 20101118
  • JP 2011077265 W 20111117

Abstract (en)

[origin: WO2012067265A1] The present invention provides a method for screening drugs for suppressing inflammasome activity, using macrophages derived from induced pluripotent stem cells (iPS cells) having mutant NLRP3 gene.

IPC 8 full level

G01N 33/50 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP US)

C12N 5/0696 (2013.01 - US); G01N 33/5055 (2013.01 - EP US); G01N 33/6869 (2013.01 - EP US); G01N 33/6872 (2013.01 - EP US); G01N 2333/545 (2013.01 - EP US); G01N 2500/10 (2013.01 - EP US)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2012067265 A1 20120524; EP 2641086 A1 20130925; EP 2641086 A4 20140514; EP 2641086 B1 20170104; EP 2641086 B9 20170816; JP 2013544349 A 20131212; JP 5924742 B2 20160525; US 2013273588 A1 20131017; US 9557321 B2 20170131

DOCDB simple family (application)

JP 2011077265 W 20111117; EP 11842110 A 20111117; JP 2013523401 A 20111117; US 201113885950 A 20111117