EP 2644205 B1 20180613 - Targeting ABCB5 for cancer therapy
Title (en)
Targeting ABCB5 for cancer therapy
Title (de)
Anzielen von ABCB5 zur Krebstherapie
Title (fr)
Ciblage d'ABCB5 pour la thérapie du cancer
Publication
Application
Priority
- US 92312807 P 20070412
- US 705907 P 20071211
- EP 08742787 A 20080411
Abstract (en)
[origin: WO2008127656A1] The invention relates to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules such as antibodies and fragments thereof.
IPC 8 full level
A61K 39/395 (2006.01); C07K 16/18 (2006.01)
CPC (source: EP US)
A61K 31/713 (2013.01 - EP US); A61K 38/47 (2013.01 - EP US); A61K 47/6851 (2017.07 - EP US); A61P 17/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 16/18 (2013.01 - US); C07K 16/28 (2013.01 - EP); C12N 15/1135 (2013.01 - US); G01N 33/574 (2013.01 - EP); G01N 33/57492 (2013.01 - US); A61K 2039/505 (2013.01 - EP US); C07K 2317/56 (2013.01 - EP US); C07K 2317/565 (2013.01 - EP US); C07K 2317/732 (2013.01 - EP US); C07K 2317/734 (2013.01 - EP US); C12N 2310/14 (2013.01 - US); C12N 2310/3513 (2013.01 - US); C12N 2320/32 (2013.01 - US); C12Y 302/02022 (2013.01 - EP US); G01N 2333/705 (2013.01 - US)
Citation (examination)
- XU JOHN L. ET AL: "Diversity in the CDR3 region of VH is sufficient for most antibody specificities", IMMUNITY, vol. 13, 1 July 2000 (2000-07-01), pages 37 - 45
- KAPLINSKY J. ET AL.: "Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cells", PNAS, 9 June 2014 (2014-06-09), pages e2622 - e2629
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008127656 A1 20081023; AU 2008239633 A1 20081023; AU 2008239633 B2 20140529; CA 2718573 A1 20081023; CA 2718573 C 20200714; CY 1116823 T1 20170315; CY 1121046 T1 20191211; DK 2155248 T3 20150914; DK 2644205 T3 20180924; EP 2155248 A1 20100224; EP 2155248 B1 20150610; EP 2644205 A1 20131002; EP 2644205 B1 20180613; EP 3431103 A1 20190123; EP 3431103 B1 20210728; ES 2547016 T3 20150930; ES 2687270 T3 20181024; HR P20150934 T1 20151106; HR P20181385 T1 20181019; HU E027593 T2 20161128; HU E039385 T2 20181228; JP 2010534191 A 20101104; JP 2014133770 A 20140724; JP 2016188248 A 20161104; JP 2018052979 A 20180405; JP 5889527 B2 20160322; JP 6268237 B2 20180124; JP 6530044 B2 20190612; LT 2644205 T 20181210; PL 2155248 T3 20151231; PL 2644205 T3 20181130; PT 2155248 E 20151023; PT 2644205 T 20181019; SI 2155248 T1 20151231; SI 2644205 T1 20181130; US 2009117117 A1 20090507; US 2011165149 A1 20110707; US 2014302031 A1 20141009; US 2016136297 A1 20160519; US 7928202 B2 20110419; US 8697072 B2 20140415; US 9266946 B2 20160223; US 9855342 B2 20180102
DOCDB simple family (application)
US 2008004715 W 20080411; AU 2008239633 A 20080411; CA 2718573 A 20080411; CY 151100784 T 20150910; CY 181100944 T 20180912; DK 08742787 T 20080411; DK 13163810 T 20080411; EP 08742787 A 20080411; EP 13163810 A 20080411; EP 18177392 A 20080411; ES 08742787 T 20080411; ES 13163810 T 20080411; HR P20150934 T 20150907; HR P20181385 T 20180828; HU E08742787 A 20080411; HU E13163810 A 20080411; JP 2010503072 A 20080411; JP 2014090150 A 20140424; JP 2016153402 A 20160804; JP 2017247931 A 20171225; LT 13163810 T 20080411; PL 08742787 T 20080411; PL 13163810 T 20080411; PT 08742787 T 20080411; PT 13163810 T 20080411; SI 200831496 T 20080411; SI 200831993 T 20080411; US 10142808 A 20080411; US 201113044854 A 20110310; US 201414251932 A 20140414; US 201615005364 A 20160125