EP 2650287 A1 20131016 - Thiazole Derivative and use thereof as VAP-1 Inhibitor
Title (en)
Thiazole Derivative and use thereof as VAP-1 Inhibitor
Title (de)
Thiazolderivate und deren Verwendung als VAP-1-Hemmer
Title (fr)
Dérivé de thiazole et son utilisation en tant qu'inhibiteur VAP-1
Publication
Application
Priority
- JP 2008021588 A 20080131
- EP 09705640 A 20090130
Abstract (en)
The present invention provides a novel thiazole derivative useful as a VAP-1 inhibitor, a pharmaceutical agent for the prophylaxis or treatment of VAP-1 associated diseases and the like. A compound represented by the formula (I): €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ R 1 -NH-X-Y-Z€ƒ€ƒ€ƒ€ƒ€ƒ(I) wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.
IPC 8 full level
A61K 31/426 (2006.01); A61K 31/427 (2006.01); C07D 277/46 (2006.01); C07D 417/06 (2006.01)
CPC (source: EP US)
A61P 3/10 (2017.12 - EP); A61P 7/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/04 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/00 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 19/08 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 27/06 (2017.12 - EP); A61P 27/12 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 277/46 (2013.01 - EP US); C07D 417/06 (2013.01 - EP US)
Citation (search report)
- [A] WO 2004067521 A1 20040812 - FUJISAWA PHARMACEUTICAL CO [JP], et al
- [A] WO 2005089755 A1 20050929 - R TECH UENO LTD [JP], et al
- [A] WO 2004087138 A1 20041014 - SUCAMPO AG [CH], et al
- [XP] WO 2008066145 A1 20080605 - R TECH UENO LTD [JP], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009096609 A1 20090806; AR 070336 A1 20100331; AU 2009209885 A1 20090806; AU 2009209885 B2 20131205; BR PI0906352 A2 20150707; CA 2712962 A1 20090806; CA 2712962 C 20160816; CN 101932568 A 20101229; CN 101932568 B 20140806; DK 2639229 T3 20150202; EP 2252604 A1 20101124; EP 2252604 B1 20140108; EP 2639229 A2 20130918; EP 2639229 A3 20131225; EP 2639229 B1 20141126; EP 2639229 B9 20150805; EP 2650287 A1 20131016; EP 2650287 B1 20141203; EP 2650287 B9 20150805; EP 2676955 A1 20131225; EP 2676955 B1 20150311; ES 2452834 T3 20140402; ES 2527014 T3 20150119; HK 1152293 A1 20120224; HK 1185348 A1 20140214; JP 2011510911 A 20110407; JP 5415430 B2 20140212; KR 101622414 B1 20160518; KR 20100112623 A 20101019; MX 2010008460 A 20100830; NZ 587205 A 20120629; PT 2639229 E 20150204; RU 2010136301 A 20120310; RU 2496776 C2 20131027; RU 2496776 C9 20141220; TW 200934488 A 20090816; TW I437986 B 20140521; US 2011015240 A1 20110120; US 8507690 B2 20130813
DOCDB simple family (application)
JP 2009052015 W 20090130; AR P090100311 A 20090130; AU 2009209885 A 20090130; BR PI0906352 A 20090130; CA 2712962 A 20090130; CN 200980103755 A 20090130; DK 13172126 T 20090130; EP 09705640 A 20090130; EP 13172126 A 20090130; EP 13172130 A 20090130; EP 13185390 A 20090130; ES 09705640 T 20090130; ES 13172126 T 20090130; HK 11106277 A 20110620; HK 13112767 A 20131114; JP 2010529187 A 20090130; KR 20107017937 A 20090130; MX 2010008460 A 20090130; NZ 58720509 A 20090130; PT 13172126 T 20090130; RU 2010136301 A 20090130; TW 98102784 A 20090123; US 86477309 A 20090130