EP 2658855 A2 20131106 - NOVEL POLYKETIDE COMPOUNDS AND METHODS OF MAKING SAME
Title (en)
NOVEL POLYKETIDE COMPOUNDS AND METHODS OF MAKING SAME
Title (de)
NEUE POLYKETIDVERBINDUNGEN UND VERFAHREN ZU IHRER HERSTELLUNG
Title (fr)
NOUVEAUX COMPOSÉS POLYCÉTIDES ET LEURS PROCÉDÉS DE FABRICATION
Publication
Application
Priority
- EP 10016223 A 20101231
- EP 2011006615 W 20111230
- EP 11813782 A 20111230
Abstract (en)
[origin: WO2012089349A2] The present invention relates to novel polyketide compounds and to enzymes and production organisms for obtaining such novel polyketide compounds. Polyketides of the present invention include non-natural, chemically active extender units, which are incorporated into the polyketide molecule by virtue of promiscuous acyl transferase domains of the polyketide synthase enzyme. Such polyketides including chemically active side chains can easily be chemically modified to yield novel polyketide drugs or drug candidates.
IPC 8 full level
C07D 407/12 (2006.01); C07D 498/04 (2006.01); C12N 9/10 (2006.01); C12N 15/52 (2006.01); C12P 17/18 (2006.01); C12P 19/62 (2006.01)
CPC (source: EP)
C07D 407/12 (2013.01); C07D 498/04 (2013.01); C12N 9/1025 (2013.01); C12N 15/52 (2013.01); C12P 17/188 (2013.01); C12P 19/62 (2013.01)
Citation (search report)
See references of WO 2012089349A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012089349 A2 20120705; WO 2012089349 A3 20121227; EP 2658855 A2 20131106
DOCDB simple family (application)
EP 2011006615 W 20111230; EP 11813782 A 20111230