EP 2661266 B1 20200916 - CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES
Title (en)
CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES
Title (de)
AUF CHEMOSENSORISCHEN REZEPTORLIGANDEN BASIERENDE THERAPIEN
Title (fr)
TRAITEMENTS À BASE DE LIGAND DE RÉCEPTEUR CHIMIOSENSORIEL
Publication
Application
Priority
- US 201161430914 P 20110107
- US 2012020548 W 20120106
Abstract (en)
[origin: US2012177730A1] Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a chemosensory receptor ligand, such as a bitter receptor ligand. Also provided herein are chemosensory receptor ligand compositions, including bitter receptor ligand compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use.
IPC 8 full level
A61K 31/4709 (2006.01); A61K 31/155 (2006.01); A61K 31/194 (2006.01); A61K 31/198 (2006.01); A61K 31/201 (2006.01); A61K 31/353 (2006.01); A61K 31/575 (2006.01); A61K 31/7016 (2006.01); A61K 31/7032 (2006.01); A61K 31/704 (2006.01); A61P 1/00 (2006.01); A61P 3/00 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61P 7/12 (2006.01); A61P 19/10 (2006.01); A61P 21/00 (2006.01); A61P 25/24 (2006.01); A61P 37/00 (2006.01)
CPC (source: EP KR US)
A61K 9/0053 (2013.01 - US); A61K 9/2054 (2013.01 - US); A61K 9/209 (2013.01 - US); A61K 9/2846 (2013.01 - US); A61K 9/4808 (2013.01 - US); A61K 31/155 (2013.01 - EP US); A61K 31/19 (2013.01 - US); A61K 31/198 (2013.01 - US); A61K 31/343 (2013.01 - KR); A61K 31/7016 (2013.01 - US); A61K 31/704 (2013.01 - US); A61K 45/06 (2013.01 - US); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); C07D 307/93 (2013.01 - KR); C07D 405/12 (2013.01 - KR); G01N 33/53 (2013.01 - KR)
Citation (examination)
- WO 2013103919 A2 20130711 - ELCELYX THERAPEUTICS INC [US]
- JOHN B. BUSE ET AL: "The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation. Results From Short-term Pharmacokinetic and 12-Week Dose-Ranging Studies", DIABETES CARE, 18 August 2015 (2015-08-18), US, pages dc150488, XP055556060, ISSN: 0149-5992, DOI: 10.2337/dc15-0488
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2012177730 A1 20120712; AU 2012204162 A1 20130801; AU 2012204162 B2 20170420; AU 2017206190 A1 20170803; AU 2017206190 B2 20190801; AU 2019253780 A1 20191107; AU 2019253780 B2 20211125; AU 2022201075 A1 20220310; BR 112013017411 A2 20160920; BR 112013017411 B1 20220322; CA 2823397 A1 20120712; CA 2823397 C 20200310; CL 2013001982 A1 20140110; CN 103597071 A 20140219; CY 1123590 T1 20220324; DK 2661266 T3 20201116; EA 039943 B1 20220330; EA 201370154 A1 20140130; EP 2661266 A2 20131113; EP 2661266 A4 20140827; EP 2661266 B1 20200916; EP 3763419 A1 20210113; ES 2834986 T3 20210621; HR P20201731 T1 20201225; HU E051738 T2 20210329; IL 227130 B 20200331; JP 2014501787 A 20140123; KR 20140035331 A 20140321; LT 2661266 T 20201210; MX 2013007884 A 20130913; PT 2661266 T 20201130; RS 61153 B1 20201231; SG 10201607085W A 20161028; SG 191855 A1 20130830; SI 2661266 T1 20210129; US 10201511 B2 20190212; US 10610500 B2 20200407; US 2014030332 A1 20140130; US 2015065578 A1 20150305; US 2015265555 A1 20150924; US 2017020829 A1 20170126; US 2019038576 A1 20190207; US 9050292 B2 20150609; US 9463170 B2 20161011; US 9962344 B2 20180508; WO 2012094636 A2 20120712; WO 2012094636 A3 20121004; ZA 201304702 B 20151125; ZA 201606957 B 20180530
DOCDB simple family (application)
US 201213345135 A 20120106; AU 2012204162 A 20120106; AU 2017206190 A 20170719; AU 2019253780 A 20191021; AU 2022201075 A 20220217; BR 112013017411 A 20120106; CA 2823397 A 20120106; CL 2013001982 A 20130705; CN 201280012454 A 20120106; CY 201101073 T 20201112; DK 12732408 T 20120106; EA 201370154 A 20120106; EP 12732408 A 20120106; EP 20191580 A 20120106; ES 12732408 T 20120106; HR P20201731 T 20201027; HU E12732408 A 20120106; IL 22713013 A 20130623; JP 2013548591 A 20120106; KR 20137020524 A 20120106; LT 12732408 T 20120106; MX 2013007884 A 20120106; PT 12732408 T 20120106; RS P20201376 A 20120106; SG 10201607085W A 20120106; SG 2013051883 A 20120106; SI 201231856 T 20120106; US 2012020548 W 20120106; US 201213978514 A 20120106; US 201314370450 A 20130105; US 201514733750 A 20150608; US 201615289713 A 20161010; US 201815971942 A 20180504; ZA 201304702 A 20130624; ZA 201606957 A 20161010