EP 2668164 A1 20131204 - NOVEL AZACOUMARIN DERIVATIVES HAVING MDR PUMP INHIBITING ACTIVITY
Title (en)
NOVEL AZACOUMARIN DERIVATIVES HAVING MDR PUMP INHIBITING ACTIVITY
Title (de)
NEUE AZACOUMARINDERIVATE MIT EINER MDR-PUMPEN-HEMMUNGSWIRKUNG
Title (fr)
NOUVEAUX DERIVES D'AZACOUMARINES PRESENTANT UNE ACTIVITE INHIBITRICE DES POMPES MDR
Publication
Application
Priority
- FR 1150674 A 20110128
- FR 2012050174 W 20120127
Abstract (en)
[origin: WO2012101388A1] The present invention relates to compounds of formula (I), where R1 and R2, identical or different, are each independently a hydrogen atom or a non-substituted or substituted (C1-C12) alkyl group; R3 is a hydrogen atom or a non-substituted or substituted (C1-C6) alkyl group; R4 is a non-substituted or substituted (C1-C12) alkyl group or an aryl or heteroaryl group, said aryl and heteroaryl groups being non-substituted or substituted; and R5 is a non-substituted or substituted (C1-C12) alkyl group; or R4 and R5 are bonded to one another by a saturated hydrocarbon chain having 3 or 4 carbon atoms, optionally in hydrated form or in the form of a salt that is acceptable for being administered to animals or plants, for the use thereof as a potentiator of the effect of an antimicrobial agent or for the use thereof as an antimicrobial agent.
IPC 8 full level
C07D 215/06 (2006.01); A61K 31/404 (2006.01)
CPC (source: EP US)
A61K 31/395 (2013.01 - EP US); A61K 31/431 (2013.01 - US); A61K 31/4704 (2013.01 - EP US); A61K 31/4709 (2013.01 - EP US); A61K 31/473 (2013.01 - EP US); A61K 31/496 (2013.01 - EP US); A61K 31/5383 (2013.01 - EP US); A61K 31/65 (2013.01 - EP US); A61K 31/7048 (2013.01 - EP US); A61K 38/14 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 215/06 (2013.01 - EP US); C07D 215/58 (2013.01 - US); C07D 401/04 (2013.01 - US); C07D 409/04 (2013.01 - US); C12Q 1/025 (2013.01 - US)
Citation (search report)
See references of WO 2012101388A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012101388 A1 20120802; EP 2668164 A1 20131204; FR 2970964 A1 20120803; FR 2970964 B1 20131213; JP 2014503578 A 20140213; US 2014038883 A1 20140206
DOCDB simple family (application)
FR 2012050174 W 20120127; EP 12706636 A 20120127; FR 1150674 A 20110128; JP 2013550935 A 20120127; US 201213981682 A 20120127