EP 2702423 B1 20191225 - METHOD FOR R2* QUANTIFICATION WITH MRI WITH CORRECTION FOR MACROSCOPIC MAGNETIC FIELD INHOMOGENEITIES
Title (en)
METHOD FOR R2* QUANTIFICATION WITH MRI WITH CORRECTION FOR MACROSCOPIC MAGNETIC FIELD INHOMOGENEITIES
Title (de)
VERFAHREN ZUR R2*-QUANTIFIZIERUNG MIT MRT MIT KORREKTUR FÜR MAKROSKOPISCHE MAGNETFELDINHOMOGENITÄTEN
Title (fr)
PROCÉDÉ DE QUANTIFICATION DE R*2 PAR IRM AVEC CORRECTION D'INHOMOGÉNÉITÉS DE CHAMP MAGNÉTIQUE MACROSCOPIQUES
Publication
Application
Priority
- US 201113089653 A 20110419
- US 2012032905 W 20120410
Abstract (en)
[origin: US2012268121A1] A method for measuring transverse relaxation rate, R2*, corrected for the presence of macroscopic magnetic field inhomogeneities with a magnetic resonance imaging (MRI) system is provided. The method accounts for additional signal decay that occurs as a result of macroscopic variations in the main magnetic field, B0, of the MRI system, and also mitigates susceptibility-based errors and introduction of increased noise in the R2* measurements. Image data are acquired by sampling multiple different echo signals occurring at respectively different echo times. A B0 field inhomogeneity map is estimated by fitting the acquired image data to an initial signal model. Using the estimated field map, a revised signal model that accounts for signal from multiple different chemical species and for signal decay resulting from macroscopic variations in the B0 field is formed. Corrected R2* values for the different chemical species are then estimated by fitting the acquired image data to the revised signal model.
IPC 8 full level
G01R 33/50 (2006.01); G01R 33/44 (2006.01); G01R 33/48 (2006.01); G01R 33/565 (2006.01)
CPC (source: EP US)
G01R 33/443 (2013.01 - EP US); G01R 33/4828 (2013.01 - EP US); G01R 33/50 (2013.01 - EP US); G01R 33/56536 (2013.01 - EP US); G01R 33/56563 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2012268121 A1 20121025; US 8854038 B2 20141007; EP 2702423 A1 20140305; EP 2702423 B1 20191225; ES 2776142 T3 20200729; WO 2012145197 A1 20121026
DOCDB simple family (application)
US 201113089653 A 20110419; EP 12720313 A 20120410; ES 12720313 T 20120410; US 2012032905 W 20120410