EP 2709446 A2 20140326 - PLATELET STORAGE USING A SIALIDASE INHIBITOR
Title (en)
PLATELET STORAGE USING A SIALIDASE INHIBITOR
Title (de)
BLUTPLÄTTCHENAUFBEWAHRUNG UNTER VERWENDUNG EINES SIALIDASE INHIBITORS
Title (fr)
STOCKAGE DE PLAQUETTES SANGUINES EN UTILISANT UN SIALIDASE INHIBITEUR
Publication
Application
Priority
- US 201161487077 P 20110517
- US 201161503984 P 20110701
- US 201261613837 P 20120321
- US 201261613876 P 20120321
- US 201213474473 A 20120517
- US 201213474627 A 20120517
- US 201213474679 A 20120517
- US 2012038462 W 20120517
Abstract (en)
[origin: WO2012158983A2] The present invention relates to a platelet additive solution (PAS) having an amount of one or more sialidase inhibitors and optionally one or more glycan-modifying agents; and one or more of PAS components that includes a salt, a citrate source, a carbon source, and any combination thereof. The present invention also relates to methods, compositions and kits for increasing the in vivo circulation time of isolated platelets by storing the platelets with one or more sialidase inhibitors. Additionally, the present invention relates to methods and compositions for reducing sialidase activity and inhibiting bacterial proliferation of one or more bacteria in a platelet product preparation from one or more donors.
IPC 8 full level
A01N 1/00 (2006.01); A61K 35/19 (2015.01)
CPC (source: EP)
A01N 1/0215 (2013.01); A01N 1/0226 (2013.01); A61K 35/19 (2013.01); A61P 7/04 (2017.12); A61P 43/00 (2017.12); Y02A 50/30 (2017.12)
Citation (search report)
See references of WO 2012158983A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012158983 A2 20121122; WO 2012158983 A3 20140103; AU 2012255137 A1 20131212; CA 2835434 A1 20121122; CN 103702556 A 20140402; EP 2709446 A2 20140326; JP 2014515352 A 20140630
DOCDB simple family (application)
US 2012038462 W 20120517; AU 2012255137 A 20120517; CA 2835434 A 20120517; CN 201280023800 A 20120517; EP 12726520 A 20120517; JP 2014511561 A 20120517