EP 2714941 A4 20141203 - COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF EPSTEIN-BARR NUCLEAR ANTIGEN 1
Title (en)
COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF EPSTEIN-BARR NUCLEAR ANTIGEN 1
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODULATION DER WIRKUNG DES EPSTEIN-BARR-NUKLEARANTIGENS 1
Title (fr)
COMPOSITIONS ET PROCÉDÉS POUR MODULATION DE L'ACTIVITÉ DE L'ANTIGÈNE 1 NUCLÉAIRE D'EPSTEIN-BARR
Publication
Application
Priority
- US 201161489293 P 20110524
- US 2012038938 W 20120522
Abstract (en)
[origin: WO2012162291A1] The present invention embraces compounds that modulate the activity of Epstein-Barr Nuclear Antigen 1 (BBNA1 ) protein and use thereof in methods for treating latent Epstein-Barr virus infection. R7 is a substituted or unsubstituted phenyl, pyridyl, or pyrimidinyl group. A pharmaceutical composition comprising a compound of the invention in admixture with a pharmaceutically acceptable carrier is also provide as are methods for modulating the activity of Epstein-Barr Nuclear Antigen 1 (EBNA1 ) protein and treating a latent EpsteinBarr virus infection with a composition of the present invention.
IPC 8 full level
C12Q 1/70 (2006.01)
CPC (source: CN EP US)
A61P 31/22 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 307/79 (2013.01 - CN EP US); C07D 307/82 (2013.01 - CN EP US); C07D 405/04 (2013.01 - EP US); C07D 405/12 (2013.01 - CN EP US); C07D 407/04 (2013.01 - EP US); C07D 413/04 (2013.01 - EP US); C07D 413/12 (2013.01 - CN EP US); C07D 417/12 (2013.01 - CN EP US)
Citation (search report)
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- [X] WO 02083654 A1 20021024 - AMGEN INC [US]
- [X] WO 02066470 A1 20020829 - AMGEN INC
- [X] WO 2010074244 A1 20100701 - TAISHO PHARMACEUTICAL CO LTD [JP], et al
- [X] US 2010093819 A1 20100415 - MORITA KOHEI [JP], et al
- [X] WO 2008118379 A2 20081002 - WYETH CORP [US], et al
- [X] WO 2009052065 A1 20090423 - SANOFI AVENTIS [FR], et al
- [X] EP 1820795 A1 20070822 - TOYAMA CHEMICAL CO LTD [JP]
- [E] EP 2589592 A1 20130508 - FUJIFILM CORP [JP]
- [IA] WO 0034238 A1 20000615 - AMERICAN HOME PROD [US]
- [X] ERLENMEYER EH ET AL: "Zur Kenntnis des 5-Aminocumarons", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA, CH, vol. 31, 1948, pages 75 - 77, XP002009857, ISSN: 0018-019X, DOI: 10.1002/HLCA.19480310114
- See references of WO 2012162291A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2012162291 A1 20121129; CN 103717757 A 20140409; EP 2714941 A1 20140409; EP 2714941 A4 20141203; JP 2014517847 A 20140724; US 2014113897 A1 20140424; US 2016168144 A1 20160616; US 9309212 B2 20160412
DOCDB simple family (application)
US 2012038938 W 20120522; CN 201280025422 A 20120522; EP 12789638 A 20120522; JP 2014512942 A 20120522; US 201214119541 A 20120522; US 201615054455 A 20160226