Global Patent Index - EP 2731603 A1

EP 2731603 A1 20140521 - STABLE DOSAGE FORMS OF ARTEROLANE AND PIPERAQUINE

Title (en)

STABLE DOSAGE FORMS OF ARTEROLANE AND PIPERAQUINE

Title (de)

STABILE DOSIERUNGSFORMEN VON ARTEROLAN UND PIPERAQUIN

Title (fr)

FORMES POSOLOGIQUES STABLES D'ARTÉROLANE ET DE PIPÉRAQUINE

Publication

EP 2731603 A1 20140521 (EN)

Application

EP 12743776 A 20120713

Priority

  • US 201113183119 A 20110714
  • IN 2703DE2011 A 20110919
  • IN 2156DE2012 A 20120712
  • IB 2012053614 W 20120713

Abstract (en)

[origin: WO2013008218A1] The field of the invention relates to stable oral dosage forms comprising, (a) cis-adamantane-2-spiro-3'-8'-[[[(2'-amino-2'-methylpropyl) amino]carbonyl]-methyl]-l',2',4'-trioxaspiro[4.5]decane hydrogen maleate (Active compound I); (b) piperaquine; and (c) one or more pharmaceutically acceptable excipients; and processes for their preparation, especially wherein the dosage form is prepared by a dry process.

IPC 8 full level

A61K 31/357 (2006.01); A61K 9/20 (2006.01); A61K 31/496 (2006.01); A61P 33/06 (2006.01)

CPC (source: EP)

A61K 9/2054 (2013.01); A61K 9/2077 (2013.01); A61K 9/2095 (2013.01); A61K 31/357 (2013.01); A61K 31/496 (2013.01); A61P 33/06 (2017.12); A61P 43/00 (2017.12); Y02A 50/30 (2017.12)

C-Set (source: EP)

  1. A61K 31/357 + A61K 2300/00
  2. A61K 31/496 + A61K 2300/00

Citation (search report)

See references of WO 2013008218A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2013008218 A1 20130117; AP 2014007413 A0 20140228; AP 3777 A 20160831; AU 2012282077 A1 20140130; CA 2850089 A1 20130117; CN 103930107 A 20140716; EA 201490233 A1 20140730; EA 201490233 A8 20150130; EP 2731603 A1 20140521; JP 2014522856 A 20140908; KR 20140053169 A 20140507; MX 2014000463 A 20140709

DOCDB simple family (application)

IB 2012053614 W 20120713; AP 2014007413 A 20120713; AU 2012282077 A 20120713; CA 2850089 A 20120713; CN 201280044576 A 20120713; EA 201490233 A 20120713; EP 12743776 A 20120713; JP 2014519689 A 20120713; KR 20147003043 A 20120713; MX 2014000463 A 20120713