Global Patent Index - EP 2739744 A1

EP 2739744 A1 20140611 - OXIDATION AND AMINATION OF SECONDARY ALCOHOLS

Title (en)

OXIDATION AND AMINATION OF SECONDARY ALCOHOLS

Title (de)

OXIDATION UND AMINIERUNG VON SEKUNDÄREN ALKOHOLEN

Title (fr)

OXYDATION ET AMINATION D'ALCOOLS SECONDAIRES

Publication

EP 2739744 A1 20140611 (DE)

Application

EP 12740366 A 20120727

Priority

  • EP 11006458 A 20110805
  • EP 12157917 A 20120302
  • EP 2012064805 W 20120727
  • EP 12740366 A 20120727

Abstract (en)

[origin: WO2013020839A1] The invention relates to a method comprising the following steps: a) providing a secondary alcohol; b) oxidizing the secondary alcohol by bringing said alcohol into contact with an NAD(P)+-dependent alcohol dehydrogenase; and c) bringing the oxidation product of step a) into contact with a transaminase, wherein the NAD(P)+-dependent alcohol dehydrogenase and/or the transaminase are/is a recombinant or isolated enzyme. The invention further relates to a whole cell catalyst for carrying out the method and to the use of such a whole cell catalyst for oxidizing a secondary alcohol.

IPC 8 full level

C12P 13/00 (2006.01); C12N 9/00 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12P 13/04 (2006.01)

CPC (source: CN EP US)

C12N 9/0006 (2013.01 - EP US); C12N 9/1096 (2013.01 - EP US); C12N 15/63 (2013.01 - EP US); C12P 13/001 (2013.01 - CN EP US); C12P 13/005 (2013.01 - CN EP US); C12P 13/04 (2013.01 - CN EP US); C12P 17/04 (2013.01 - US); C12Y 101/01001 (2013.01 - EP US); C12Y 206/01 (2013.01 - EP US); C12Y 206/01018 (2013.01 - EP US)

Citation (search report)

See references of WO 2013020839A1

Citation (examination)

  • EDEGGER K ET AL: "Biocatalytic oxidation of sec-alcohols via hydrogen transfer", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, ELSEVIER, AMSTERDAM, NL, vol. 251, no. 1-2, 17 May 2006 (2006-05-17), pages 66 - 70, XP028015270, ISSN: 1381-1169, [retrieved on 20060517], DOI: 10.1016/J.MOLCATA.2006.02.007
  • JOERG H SCHRITTWIESER ET AL: "Recent biocatalytic oxidationreduction cascades", CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 15, no. 2, April 2011 (2011-04-01), pages 249 - 256, XP028187359, ISSN: 1367-5931, [retrieved on 20101111], DOI: 10.1016/J.CBPA.2010.11.010

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2013020839 A1 20130214; BR 112014002732 A2 20170613; BR 112014002732 A8 20170620; CA 2844090 A1 20130214; CN 103827309 A 20140528; CN 107034247 A 20170811; EP 2739744 A1 20140611; JP 2014524245 A 20140922; RU 2014108194 A 20150910; US 2014308717 A1 20141016

DOCDB simple family (application)

EP 2012064805 W 20120727; BR 112014002732 A 20120727; CA 2844090 A 20120727; CN 201280048033 A 20120727; CN 201710111933 A 20120727; EP 12740366 A 20120727; JP 2014524330 A 20120727; RU 2014108194 A 20120727; US 201214237121 A 20120727