EP 2753937 A1 20140716 - CHARACTERIZATION OF CHO-MIF GENE AND PROTEIN, AND USE THEREOF
Title (en)
CHARACTERIZATION OF CHO-MIF GENE AND PROTEIN, AND USE THEREOF
Title (de)
CHARAKTERISIERUNG VON CHO-MIF-GENEN UND PROTEINEN UND VERWENDUNG DAVON
Title (fr)
CARACTÉRISATION DU GÈNE ET DE LA PROTÉINE CHO-MIF, ET SON UTILISATION
Publication
Application
Priority
- US 201161545047 P 20111007
- EP 2012069602 W 20121004
Abstract (en)
[origin: WO2013050457A1] The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.
IPC 8 full level
G01N 33/68 (2006.01); C07K 16/24 (2006.01); C12N 5/10 (2006.01)
CPC (source: EP US)
C07K 16/24 (2013.01 - EP US); C12N 5/00 (2013.01 - US); C12N 9/90 (2013.01 - EP US); C12Y 503/03012 (2013.01 - EP US); G01N 33/6854 (2013.01 - EP US); G01N 33/6863 (2013.01 - EP US); C07K 2317/14 (2013.01 - US); C12N 2510/00 (2013.01 - US); G01N 2333/52 (2013.01 - EP US)
Citation (search report)
See references of WO 2013050457A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2013050457 A1 20130411; AR 088245 A1 20140521; AU 2012327159 A1 20130516; AU 2012327159 B2 20150326; EP 2753937 A1 20140716; EP 2753937 B1 20180117; HK 1199494 A1 20150703; JP 2014530361 A 20141117; TW 201319571 A 20130516; TW 201639957 A 20161116; TW I569013 B 20170201; US 2014287443 A1 20140925; US 2017210794 A1 20170727; US 9465037 B2 20161011
DOCDB simple family (application)
EP 2012069602 W 20121004; AR P120103714 A 20121005; AU 2012327159 A 20121004; EP 12770473 A 20121004; HK 14113002 A 20141227; JP 2014533887 A 20121004; TW 101137029 A 20121005; TW 105123852 A 20121005; US 201214350187 A 20121004; US 201615252100 A 20160830