Global Patent Index - EP 2756092 A4

EP 2756092 A4 20151028 - METHODS OF MAKING CELLS, TISSUES, AND ANTIBODIES

Title (en)

METHODS OF MAKING CELLS, TISSUES, AND ANTIBODIES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON ZELLEN, GEWEBEN UND ANTIKÖRPERN

Title (fr)

PROCÉDÉS DE FABRICATION DE CELLULES, DE TISSUS ET D'ANTICORPS

Publication

EP 2756092 A4 20151028 (EN)

Application

EP 12832552 A 20120914

Priority

  • US 201161535897 P 20110916
  • US 2012055331 W 20120914

Abstract (en)

[origin: WO2013040307A1] Methods of making cells, tissues and antibodies, especially human cells, tissues and antibodies are disclosed. Human antibodies and other human cell and tissue types are generated in a human teratoma in a non-human host species. Such antibodies, cells, and tissues are then isolated for therapeutic or diagnostic use, or for screening assays.

IPC 8 full level

C12P 21/00 (2006.01); A01K 67/00 (2006.01); A01K 67/027 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 5/0781 (2010.01); C12N 5/0783 (2010.01); C12N 5/0786 (2010.01); C12N 5/0787 (2010.01); C12N 5/0789 (2010.01)

CPC (source: EP)

A01K 67/0271 (2013.01); C07K 16/00 (2013.01); C07K 16/2887 (2013.01); C12N 5/0635 (2013.01); C12N 5/0636 (2013.01); C12N 5/0642 (2013.01); C12N 5/0645 (2013.01); C12N 5/0647 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); C07K 2317/21 (2013.01); C12N 2506/45 (2013.01)

Citation (search report)

  • [A] WO 2011071085 A1 20110616 - UNIV TOKYO [JP], et al
  • [A] BONGKUM CHOI ET AL: "Human B Cell Development and Antibody Production in Humanized NOD/SCID/IL-2RÎ (NSG) Mice Conditioned by Busulfan", JOURNAL OF CLINICAL IMMUNOLOGY, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 31, no. 2, 28 October 2010 (2010-10-28), pages 253 - 264, XP019910966, ISSN: 1573-2592, DOI: 10.1007/S10875-010-9478-2
  • [T] LONBERG ET AL: "Fully human antibodies from transgenic mouse and phage display platforms", CURRENT OPINION IN IMMUNOLOGY, ELSEVIER, OXFORD, GB, vol. 20, no. 4, 1 August 2008 (2008-08-01), pages 450 - 459, XP025771204, ISSN: 0952-7915, [retrieved on 20080721], DOI: 10.1016/J.COI.2008.06.004
  • [T] NAO SUZUKI ET AL: "Generation of Engraftable Hematopoietic Stem Cells From Induced Pluripotent Stem Cells by Way of Teratoma Formation", MOLECULAR THERAPY, vol. 21, no. 7, 14 May 2013 (2013-05-14), pages 1424 - 1431, XP055213298, ISSN: 1525-0016, DOI: 10.1038/mt.2013.71
  • [T] G. AMABILE ET AL: "In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells", BLOOD, vol. 121, no. 8, 4 December 2012 (2012-12-04), pages 1255 - 1264, XP055063362, ISSN: 0006-4971, DOI: 10.1182/blood-2012-06-434407
  • See also references of WO 2013040307A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2013040307 A1 20130321; EP 2756092 A1 20140723; EP 2756092 A4 20151028

DOCDB simple family (application)

US 2012055331 W 20120914; EP 12832552 A 20120914