EP 2786750 B2 20230628 - AGENT FOR REDUCING ADVERSE SIDE EFFECTS OF KINASE INHIBITOR
Title (en)
AGENT FOR REDUCING ADVERSE SIDE EFFECTS OF KINASE INHIBITOR
Title (de)
MITTEL ZUR VERRINGERUNG UNERWÜNSCHTER NEBENWIRKUNGEN VON KINASEHEMMERN
Title (fr)
AGENT DESTINÉ À LA RÉDUCTION D'EFFETS SECONDAIRES NÉGATIFS D'UN INHIBITEUR DE KINASE
Publication
Application
Priority
- JP 2011264687 A 20111202
- JP 2012081213 W 20121130
Abstract (en)
[origin: EP2786750A1] The present invention relates to an agent for reducing the side effects of kinase inhibitors, the agent containing at least one branched-chain amino acid selected from among isoleucine, leucine and valine or a salt thereof as an active ingredient, and also relates to an anticancer medicine containing at least one branched-chain amino acid selected from among isoleucine, leucine and valine or a salt thereof, and a kinase inhibitor.
IPC 8 full level
A61K 31/198 (2006.01); A61K 31/44 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP US)
A61K 31/198 (2013.01 - EP US); A61K 31/416 (2013.01 - EP US); A61K 31/4365 (2013.01 - EP US); A61K 31/44 (2013.01 - EP US); A61K 31/4439 (2013.01 - EP US); A61K 31/47 (2013.01 - EP US); A61K 31/496 (2013.01 - EP US); A61K 31/506 (2013.01 - EP US); A61K 31/517 (2013.01 - EP US); A61K 31/5377 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 1/16 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (opposition)
Opponent :
- WO 2004026294 A1 20040401 - NOVARTIS NUTRITION AG [CH], et al
- COLLELA ET AL.: "Efficacy of a spray compound containing a pool of collagen precursor synthetic amino acids (L-proline, L-leucine, L-lysine and glycine) combined with sodium hyaluronate to manage chemo/radiotherapy-induced oral mucositis: preliminary data of an open clinical triaf?", INT. J. IMMUNOPATHOLOGY AND PHARMACOLOGY, vol. 23, no. 1, 2010, pages 143 - 151
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 2786750 A1 20141008; EP 2786750 A4 20150408; EP 2786750 B1 20160608; EP 2786750 B2 20230628; CN 104023715 A 20140903; CN 104023715 B 20161026; JP 2015131865 A 20150723; JP 5788527 B2 20150930; JP WO2013081154 A1 20150427; KR 101909433 B1 20181018; KR 20140087037 A 20140708; US 2014275183 A1 20140918; WO 2013081154 A1 20130606
DOCDB simple family (application)
EP 12852587 A 20121130; CN 201280058350 A 20121130; JP 2012081213 W 20121130; JP 2013547258 A 20121130; JP 2015090705 A 20150427; KR 20147014464 A 20121130; US 201414290275 A 20140529