EP 2793583 A1 20141029 - NOVEL NEUROMODULATORY COMPOUNDS
Title (en)
NOVEL NEUROMODULATORY COMPOUNDS
Title (de)
NEUARTIGE NEUROMODULATORISCHE VERBINDUNGEN
Title (fr)
NOUVEAUX COMPOSÉS NEUROMODULATEURS
Publication
Application
Priority
- US 201161578778 P 20111221
- US 2012043686 W 20120622
Abstract (en)
[origin: US2013165469A1] Provided herein are novel neuromodulatory compounds and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine and Parkinson's disease, using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT1D and/or the 5-HT1B receptor, without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the adrenergic alpha2A and/or the alpha2B receptors using the compounds and compositions disclosed herein. In other embodiments, provided herein are methods of agonizing dopaminergic D2 receptors and/or antagonizing or inhibiting activity of receptors such as the 5-HT2 receptors using the compounds and compositions disclosed herein.
IPC 8 full level
C07D 457/12 (2006.01); A61K 31/48 (2006.01)
CPC (source: EP US)
A61K 31/48 (2013.01 - EP US); A61P 25/06 (2017.12 - EP); A61P 25/16 (2017.12 - EP); C07D 457/12 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2013165469 A1 20130627; US 8946420 B2 20150203; AU 2012355983 A1 20150122; CA 2859175 A1 20130627; EP 2793583 A1 20141029; EP 2793583 A4 20150812; IL 233002 A0 20140731; SG 10201506202R A 20150929; SG 11201403433P A 20140730; US 2015148371 A1 20150528; WO 2013095708 A1 20130627
DOCDB simple family (application)
US 201213531427 A 20120622; AU 2012355983 A 20120622; CA 2859175 A 20120622; EP 12860106 A 20120622; IL 23300214 A 20140608; SG 10201506202R A 20120622; SG 11201403433P A 20120622; US 2012043686 W 20120622; US 201514607325 A 20150128