EP 2804593 A1 20141126 - PROCESS FOR PRODUCING A SOLID PHARMACEUTICAL COMPOSITION COMPRISING THE ACTIVE INGREDIENT RASAGILINE
Title (en)
PROCESS FOR PRODUCING A SOLID PHARMACEUTICAL COMPOSITION COMPRISING THE ACTIVE INGREDIENT RASAGILINE
Title (de)
VERFAHREN ZUR HERSTELLUNG EINER FESTEN PHARMAZEUTISCHEN ZUSAMMENSETZUNG, ENTHALTEND DEN WIRKSTOFF RASAGILIN
Title (fr)
PROCÉDÉ PERMETTANT DE PRÉPARER UNE COMPOSITION PHARMACEUTIQUE SOLIDE CONTENANT LE PRINCIPE ACTIF RASAGILINE
Publication
Application
Priority
- DE 102012000786 A 20120118
- DE 2013000024 W 20130116
Abstract (en)
[origin: WO2013107441A1] The present invention relates to a process for producing a solid pharmaceutical composition comprising the active ingredient rasagiline, comprising: dissolving a pharmaceutically acceptable rasagiline salt in an aqueous solvent to obtain a rasagiline salt solution; admixing a solid carrier with the rasagiline salt solution. In order to provide a process by means of which compositions in which the rasagiline has elevated stability are obtainable and the composition can correspondingly be stored for longer, it is proposed that the pH of the rasagiline salt solution be adjusted to a value of less than 3.5 by means of a pharmaceutically acceptable acid.
IPC 8 full level
A61K 9/20 (2006.01); A61K 31/135 (2006.01); A61P 25/16 (2006.01)
CPC (source: EP)
A61K 9/1635 (2013.01); A61K 9/167 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/2077 (2013.01); A61K 31/135 (2013.01); A61P 25/16 (2017.12)
Citation (search report)
See references of WO 2013107441A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DE 102012000786 A1 20130718; EP 2804593 A1 20141126; RU 2014128296 A 20160310; WO 2013107441 A1 20130725
DOCDB simple family (application)
DE 102012000786 A 20120118; DE 2013000024 W 20130116; EP 13702727 A 20130116; RU 2014128296 A 20130116