EP 2810050 A1 20141210 - MULTICOLOUR EXCITATION MODULE FOR A MULTIPHOTON IMAGING SYSTEM, AND ASSOCIATED METHOD AND SYSTEM
Title (en)
MULTICOLOUR EXCITATION MODULE FOR A MULTIPHOTON IMAGING SYSTEM, AND ASSOCIATED METHOD AND SYSTEM
Title (de)
MEHRFARBIGES ERREGERMODUL FÜR EIN MULTIPHOTONENABBILDUNGSSYSTEM SOWIE ZUGEHÖRIGES VERFAHREN UND SYSTEM
Title (fr)
MODULE D'EXCITATION MULTI-COULEURS POUR UN SYSTEME D'IMAGERIE MULTI-PHOTONIQUE, SYSTEME ET PROCEDE ASSOCIES
Publication
Application
Priority
- FR 1250990 A 20120202
- EP 2013052002 W 20130201
Abstract (en)
[origin: WO2013113861A1] The present invention concerns a multicolour excitation module 1 for a multiphoton imaging system 100. Such a module is used for imaging a sample 7 comprising at least three chromophores. The module 1 comprises: a first femtosecond laser source 2, emitting a first excitation beam 20; a second femtosecond laser source 3 emitting a second excitation beam 30. The first excitation beam 20 comprises a so-called "pumping" portion, said pumping portion acting as a pump beam to synchronously excite the second laser source 3, and a so-called "excitation" portion. An optical delay line 4 is arranged to spatially and temporally superpose the second excitation beam 30 and the excitation portion of the first excitation beam, so as to excite at least a third of the chromophores by multiphoton absorption, said absorbed photons coming from the first and second excitation beams 20, 30. The invention also concerns the complete multiphoton imaging system 100, and a method implemented in this module 1.
IPC 8 full level
G01N 21/64 (2006.01); G02B 21/00 (2006.01)
CPC (source: EP US)
G01N 21/6456 (2013.01 - US); G01N 21/6458 (2013.01 - EP US); G02B 17/023 (2013.01 - EP US); G02B 21/16 (2013.01 - EP US); G01N 21/3151 (2013.01 - US); G01N 21/6402 (2013.01 - EP US); G01N 2021/6419 (2013.01 - EP US); G01N 2201/06113 (2013.01 - US); G01N 2201/0668 (2013.01 - US); G01N 2201/0697 (2013.01 - EP US)
Citation (search report)
See references of WO 2013113861A1
Citation (examination)
CAMPAGNOLA P J ET AL: "High-resolution nonlinear optical imaging of live cells by second harmonic generation", BIOPHYSICAL JOURNAL, ELSEVIER, AMSTERDAM, NL, vol. 77, no. 6, 1 December 1999 (1999-12-01), pages 3341 - 3349, XP002248209, ISSN: 0006-3495
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2013113861 A1 20130808; EP 2810050 A1 20141210; FR 2986668 A1 20130809; FR 2986668 B1 20140221; JP 2015511312 A 20150416; JP 6254096 B2 20171227; US 2014367591 A1 20141218
DOCDB simple family (application)
EP 2013052002 W 20130201; EP 13705115 A 20130201; FR 1250990 A 20120202; JP 2014555215 A 20130201; US 201314376040 A 20130201