EP 2812451 A4 20160106 - METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ROS1 FOR DIAGNOSING AND TREATING CANCER
Title (en)
METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ROS1 FOR DIAGNOSING AND TREATING CANCER
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN IN ZUSAMMENHANG MIT ROS1-FUSIONEN ZUR DIAGNOSTIZIERUNG UND BEHANDLUNG VON KREBS
Title (fr)
PROCÉDÉS ET COMPOSITIONS CONCERNANT DES FUSIONS DE ROS1 POUR DIAGNOSTIQUER ET TRAITER LE CANCER
Publication
Application
Priority
- US 201261596720 P 20120208
- US 2013025345 W 20130208
Abstract (en)
[origin: WO2013119950A2] Disclosed are methods and compositions for detecting the presence of a cancer in a subject and assessing the efficacy of treatments for the same. The disclosed method use real-time polymerase chain reaction, reverse transcription polymerase chain reaction (RT-PCR), in situ hybridization and/or multiplex polymerase chain reaction techniques to detect the presence of point mutations, truncations, or fusions of ROS1.
IPC 8 full level
C12Q 1/68 (2006.01)
CPC (source: CN EP)
C12Q 1/6886 (2013.01 - CN EP); C12Q 2600/156 (2013.01 - CN EP); C12Q 2600/158 (2013.01 - CN EP)
Citation (search report)
- [XI] WO 2007084631 A2 20070726 - CELL SIGNALING TECHNOLOGY INC [US], et al
- [XI] WO 2011146945 A2 20111124 - CELL SIGNALING TECHNOLOGY INC, et al
- [XI] CHENGUANG LI ET AL: "Spectrum of Oncogenic Driver Mutations in Lung Adenocarcinomas from East Asian Never Smokers", PLOS ONE, vol. 6, no. 11, 30 November 2011 (2011-11-30), pages e28204, XP055209333, DOI: 10.1371/journal.pone.0028204
- See references of WO 2013119950A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2013119950 A2 20130815; WO 2013119950 A3 20141113; AU 2013216904 A1 20140828; CN 104364391 A 20150218; EP 2812451 A2 20141217; EP 2812451 A4 20160106; JP 2015508644 A 20150323
DOCDB simple family (application)
US 2013025345 W 20130208; AU 2013216904 A 20130208; CN 201380013401 A 20130208; EP 13746869 A 20130208; JP 2014556726 A 20130208