EP 2822926 A4 20151104 - SELECTIVE HISTONE DEACTYLASE 6 INHIBITORS
Title (en)
SELECTIVE HISTONE DEACTYLASE 6 INHIBITORS
Title (de)
SELEKTIVE HISTON-DEACTYLASE-6-HEMMER
Title (fr)
INHIBITEURS SÉLECTIFS D'HISTONE DÉSACÉTYLASE 6
Publication
Application
Priority
- US 201261607803 P 20120307
- US 201261618150 P 20120330
- US 201261648946 P 20120518
- US 201261651595 P 20120525
- US 201261651896 P 20120525
- US 201261674942 P 20120724
- US 201261715379 P 20121018
- US 2013029521 W 20130307
Abstract (en)
[origin: WO2013134467A1] Disclosed are selective histone deactylase inhibitors (HDACi) that having Formula (I). Methods of making and using these inhibitors for the treatment of cancer, in particular melanoma are also disclosed.
IPC 8 full level
C07C 275/34 (2006.01); A61K 31/155 (2006.01); C07C 275/28 (2006.01); C07D 209/08 (2006.01)
CPC (source: EP)
A61K 31/437 (2013.01); A61K 45/06 (2013.01); A61P 17/00 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07C 275/24 (2013.01); C07C 275/28 (2013.01); C07C 275/30 (2013.01); C07C 275/34 (2013.01); C07D 209/14 (2013.01); C07D 213/75 (2013.01); C07D 233/72 (2013.01); C07D 233/78 (2013.01); C07D 235/26 (2013.01); C07D 239/42 (2013.01); C07D 261/14 (2013.01); C07D 295/13 (2013.01)
Citation (search report)
- [XP] WO 2012178208 A2 20121227 - STEVENS INST TECHNOLOGY [US], et al
- [X] WO 2006017216 A1 20060216 - MERCK & CO INC [US], et al
- [XI] J CHANG ET AL: "Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide", BRITISH JOURNAL OF CANCER, vol. 106, no. 1, 3 January 2012 (2012-01-03), pages 116 - 125, XP055212706, ISSN: 0007-0920, DOI: 10.1038/bjc.2011.532
- [XI] KATO YUKIHIKO ET AL: "Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma", MOLECULAR CANCER THERAPEUTICS, AMERICAN ASSOCIATION OF CANCER RESEARCH, US, vol. 6, no. 1, 1 January 2007 (2007-01-01), pages 70 - 81, XP002490438, ISSN: 1535-7163, DOI: 10.1158/1535-7163.MCT-06-0125
- [XI] ULRIKE HEIDER ET AL: "Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma", EUROPEAN JOURNAL OF HAEMATOLOGY, vol. 76, no. 1, 1 January 2006 (2006-01-01), pages 42 - 50, XP055212734, ISSN: 0902-4441, DOI: 10.1111/j.1600-0609.2005.00546.x
- See references of WO 2013134467A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2013134467 A1 20130912; AU 2013230881 A1 20141030; CA 2866707 A1 20130912; EP 2822926 A1 20150114; EP 2822926 A4 20151104; JP 2015510886 A 20150413; JP 6233812 B2 20171122
DOCDB simple family (application)
US 2013029521 W 20130307; AU 2013230881 A 20130307; CA 2866707 A 20130307; EP 13758416 A 20130307; JP 2014561101 A 20130307