EP 2823307 A4 20150729 - METHODS AND KITS FOR ANALYZING BIOMARKERS IN A SIGNAL TRANSDUCTION PATHWAY
Title (en)
METHODS AND KITS FOR ANALYZING BIOMARKERS IN A SIGNAL TRANSDUCTION PATHWAY
Title (de)
VERFAHREN UND KITS ZUR ANALYSE VON BIOMARKERN IN EINEM SIGNALTRANSDUKTIONSWEG
Title (fr)
PROCÉDÉS ET TROUSSES POUR L'ANALYSE DE BIOMARQUEURS DANS UNE VOIE DE TRANSDUCTION DES SIGNAUX
Publication
Application
Priority
- US 201261608348 P 20120308
- US 201261617833 P 20120330
- US 201261661388 P 20120619
- US 201261668497 P 20120706
- US 201261668490 P 20120706
- US 201261669956 P 20120710
- US 2013029891 W 20130308
Abstract (en)
[origin: WO2013134647A1] Provided are methods and kits for analyzing biomarkers in one or more signal transduction pathways in a cell, that permit simultaneous analysis of more than one biomarker and/or more than one signal transduction pathway. Further provided are methods for detecting whether a cell treated with an agent targeting a targeted biomarker is responding to the agent, or whether the cell is developing resistance to the agent, and methods for determining which biomarker to target in a diseased or damaged cell, or which pathway an agent is targeting in an agent-treated cell. Also provided are kits for carrying out the described methods.
IPC 8 full level
G01N 33/543 (2006.01); G01N 29/02 (2006.01); G01N 29/22 (2006.01)
CPC (source: EP US)
G01N 33/54306 (2013.01 - EP US); G01N 2291/0255 (2013.01 - EP US); G01N 2333/5756 (2013.01 - US); G01N 2333/91205 (2013.01 - US); G01N 2333/96433 (2013.01 - US); G01N 2446/20 (2013.01 - EP US); G01N 2800/52 (2013.01 - US)
Citation (search report)
- [XDI] YAN Z.H. ET AL.: "Analysis of two pharmacodynamic biomarkers using acoustic micro magnetic particles on the ViBE bioanalyzer", ANAL. BIOCHEM., vol. 410, no. 1, 1 March 2011 (2011-03-01), pages 13 - 18, XP027590143
- [A] TAOUJI S. ET AL.: "Current screens based on the AlphaScreen (TM) technology for deciphering cell signalling pathways", CURR. GENOMICS, vol. 10, no. 2, April 2009 (2009-04-01), pages 93 - 101, XP002660263
- [T] DICKERSON W.M. ET AL.: "Measurement of downstream kinase activity modulation as indicator of epidermal growth factor receptor inhibitor efficacy", ANAL. BIOCHEM., vol. 448, 6 December 2013 (2013-12-06), pages 65 - 67, XP028609162
- See references of WO 2013134647A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2013134647 A1 20130912; EP 2823307 A1 20150114; EP 2823307 A4 20150729; US 2015057180 A1 20150226
DOCDB simple family (application)
US 2013029891 W 20130308; EP 13757226 A 20130308; US 201414478637 A 20140905