EP 2826474 B1 20210526 - USE OF SUBSTITUTED DIPHENYLAMINE COMPOUNDS IN PREPARING ANTI-TUMOUR DRUGS
Title (en)
USE OF SUBSTITUTED DIPHENYLAMINE COMPOUNDS IN PREPARING ANTI-TUMOUR DRUGS
Title (de)
VERWENDUNG SUBSTITUIERTER DIPHENYLAMINVERBINDUNGEN ZUR HERSTELLUNG VON ARZNEIMITTELN MIT ANTITUMORWIRKUNG
Title (fr)
UTILISATION DE COMPOSÉS DE DIPHÉNYLAMINE DANS LA PRÉPARATION DES MÉDICAMENTS ANTI-TUMEURS
Publication
Application
Priority
- CN 201210067267 A 20120314
- CN 201210067595 A 20120314
- CN 2013072232 W 20130306
Abstract (en)
[origin: EP2826474A1] The invention relates to substituted diphenylamine compounds using as antitumor agents. The structure of the compounds is represented as the general formula (I): The groups are as defined as specification. The compound represented by formula (I) showed potent antitumor activity, especially to cure or alleviate the cancer causing by cancer cells of human tissue or organ. The preferred cancers are: colon cancer, liver cancer, lymph cancer, lung cancer, esophageal cancer, breast cancer, central nervous system cancer, melanoma, ovarian cancer, cervical cancer, renal cancer, leukemia, prostatic cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharynx cancer or stomach cancer.
IPC 8 full level
A61K 31/136 (2006.01); A61K 31/277 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C07C 205/06 (2006.01); C07C 205/37 (2006.01); C07C 211/55 (2006.01); C07C 211/56 (2006.01); C07C 217/92 (2006.01); C07C 229/58 (2006.01); C07C 233/65 (2006.01); C07C 255/57 (2006.01); C07C 255/58 (2006.01); C07C 255/59 (2006.01); C07C 323/36 (2006.01); C07D 213/643 (2006.01)
CPC (source: EP US)
A61K 31/136 (2013.01 - EP US); A61K 31/277 (2013.01 - EP US); A61P 1/04 (2017.12 - EP); A61P 1/16 (2017.12 - EP); A61P 1/18 (2017.12 - EP); A61P 11/02 (2017.12 - EP); A61P 11/04 (2017.12 - EP); A61P 13/08 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 19/08 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); C07C 205/06 (2013.01 - US); C07C 205/37 (2013.01 - US); C07C 211/56 (2013.01 - EP US); C07C 217/92 (2013.01 - EP US); C07C 229/58 (2013.01 - EP US); C07C 233/65 (2013.01 - EP US); C07C 255/57 (2013.01 - EP US); C07C 255/58 (2013.01 - US); C07C 255/59 (2013.01 - EP US); C07C 323/36 (2013.01 - EP US); C07D 213/643 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 2826474 A1 20150121; EP 2826474 A4 20150408; EP 2826474 B1 20210526; AR 090334 A1 20141105; CA 2859842 A1 20130919; CA 2859842 C 20161108; CN 104136021 A 20141105; CN 104136021 B 20160420; JP 2015511591 A 20150420; JP 5959670 B2 20160802; KR 101599300 B1 20160303; KR 20140097444 A 20140806; TW 201336808 A 20130916; TW I516259 B 20160111; US 2015011628 A1 20150108; US 9376376 B2 20160628; WO 2013135147 A1 20130919
DOCDB simple family (application)
EP 13761044 A 20130306; AR P130100821 A 20130313; CA 2859842 A 20130306; CN 2013072232 W 20130306; CN 201380007479 A 20130306; JP 2014561274 A 20130306; KR 20147017304 A 20130306; TW 102108792 A 20130313; US 201314376074 A 20130306