EP 2836515 A1 20150218 - LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME
Title (en)
LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME
Title (de)
ZUSAMMENSETZUNGEN AUS SCHWACH SAUREN SPEZIES UND VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG DAVON
Title (fr)
COMPOSITIONS D'ESPÈCES FAIBLEMENT ACIDES ET LEURS PROCÉDÉS DE PRODUCTION ET D'UTILISATION
Publication
Application
Priority
- US 2013031485 W 20130314
- US 2013031681 W 20130314
- US 2013065749 W 20131018
Abstract (en)
[origin: WO2014158231A1] The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided.
IPC 8 full level
C07K 16/24 (2006.01)
CPC (source: EP)
A61P 37/02 (2017.12); C07K 1/165 (2013.01); C07K 1/18 (2013.01); C07K 1/22 (2013.01); C07K 16/241 (2013.01)
Citation (search report)
See references of WO 2014158231A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014158231 A1 20141002; AU 2013384204 A1 20150604; AU 2013384204 B2 20170316; BR 112015017307 A2 20171121; CA 2899308 A1 20141002; CA 2899308 C 20170418; CA 2926301 A1 20141002; CA 2926384 A1 20141002; EP 2836515 A1 20150218; HK 1206755 A1 20160115; KR 20150129033 A 20151118; SG 11201504260U A 20151029
DOCDB simple family (application)
US 2013065749 W 20131018; AU 2013384204 A 20131018; BR 112015017307 A 20131018; CA 2899308 A 20131018; CA 2926301 A 20131018; CA 2926384 A 20131018; EP 13786072 A 20131018; HK 15107319 A 20150730; KR 20157029562 A 20131018; SG 11201504260U A 20131018