EP 2842573 A1 20150304 - Monoclonal antibodies to Fibroblast Growth Factor receptor 2

Title (en)

Monoclonal antibodies to Fibroblast Growth Factor receptor 2

Title (de)

Monoklonale Antikörper gegen den Fibroblasten-Wachstumsfaktor-Rezeptor 2

Title (fr)

Anticorps monoclonaux dirigés contre le récepteur 2 du facteur de croissance des fibroblastes

Publication

EP 2842573 A1 20150304 (EN)

Application

EP 14188785 A 20091106

Priority

US 11268608 P 20081107
US 16487009 P 20090330
EP 09825523 A 20091106

Abstract (en)

The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.

IPC 8 full level

C07K 16/28 (2006.01); A61P 35/00 (2006.01)

CPC (source: EP US)

A61P 1/00 (2018.01 - EP); A61P 1/04 (2018.01 - EP); A61P 35/00 (2018.01 - EP); C07K 16/2863 (2013.01 - EP US); G01N 33/57492 (2013.01 - US); A61K 2039/505 (2013.01 - EP US); C07K 2317/24 (2013.01 - EP US); C07K 2317/33 (2013.01 - EP US); C07K 2317/51 (2013.01 - US); C07K 2317/565 (2013.01 - US); C07K 2317/92 (2013.01 - EP US); G01N 2333/71 (2013.01 - US)

Citation (applicant)

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Citation (search report)

[XI] US 2007248605 A1 20071025 - HESTIR KEVIN [US], et al
[ID] WEI PING ET AL: "Generation and characterization of monoclonal antibodies to human keratinocyte growth factor receptor", HYBRIDOMA, vol. 25, no. 3, June 2006 (2006-06-01), pages 115 - 124, XP002673993, ISSN: 1554-0014
[A] MASAYUKI TAKEDA ET AL: "AZD2171 Shows Potent Antitumor Activity Against Gastric Cancer Over- Expressing Fibroblast Growth Factor Receptor 2/Keratinocyte Growth Factor Receptor", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 13, no. 10, 15 May 2007 (2007-05-15), pages 3051 - 3057, XP008138953, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-06-2743
[T] ZHAO WEI-MENG ET AL: "Monoclonal Antibodies to Fibroblast Growth Factor Receptor 2 Effectively Inhibit Growth of Gastric Tumor Xenografts", CLINICAL CANCER RESEARCH, vol. 16, no. 23, December 2010 (2010-12-01), pages 5750 - 5758, XP002673994, ISSN: 1078-0432

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

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DOCDB simple family (application)

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