EP 2866791 A4 20160420 - NOVEL COMPOSITIONS AND USES OF ANTI-HYPERTENSION AGENTS FOR CANCER THERAPY
Title (en)
NOVEL COMPOSITIONS AND USES OF ANTI-HYPERTENSION AGENTS FOR CANCER THERAPY
Title (de)
NEUARTIGE ZUSAMMENSETZUNGEN UND VERWENDUNGEN BLUTDRUCKSENKENDER MITTEL ZUR KREBSTHERAPIE
Title (fr)
NOUVELLES COMPOSITIONS ET UTILISATIONS D'AGENTS ANTIHYPERTENSEURS POUR THÉRAPIE ANTICANCÉREUSE
Publication
Application
Priority
- US 201261643487 P 20120507
- US 201313834094 A 20130315
- US 2013039901 W 20130507
Abstract (en)
[origin: WO2013169739A1] Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., a cancer therapy) are disclosed. In one embodiment, methods and compositions for treating or preventing a cancer (e.g., a solid tumor such as a desmoplastic tumor) by administering to a subject an anti-hypertensive agent, as a single agent or in combination with a microenvironment modulator and/or a therapy, e.g., a cancer therapy (for example, a therapeutic agent or therapy, including immunotherapy (e.g., antibodies, vaccine, cell-based), nanotherapeutics, radiation therapy, photodynamic therapy, low molecular weight chemotherapeutics, molecularly targeted therapeutics and/or oxygen radical) are disclosed.
IPC 8 full level
A61K 9/14 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP)
A61K 9/51 (2013.01); A61K 31/4178 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2017.12)
Citation (search report)
- [XP] WO 2012068531 A2 20120524 - GEN HOSPITAL CORP [US], et al
- [X] CN 101612400 A 20091230 - ZHILONG CHEN
- [X] NOGUCHI R ET AL: "Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities", ONCOLOGY REPORTS, SPANDIDOS PUBLICATIONS, GR, vol. 22, no. 2, 1 August 2009 (2009-08-01), pages 355 - 360, XP002744523, ISSN: 1021-335X, [retrieved on 20090801], DOI: 10.3892/OR_00000445
- [X] RHODES DANIEL R ET AL: "AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 106, no. 25, 23 June 2009 (2009-06-23), pages 10284 - 10289, XP002592235, ISSN: 0027-8424, [retrieved on 20090601], DOI: 10.1073/PNAS.0900351106
- See references of WO 2013169739A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2013169739 A1 20131114; AU 2013259772 A1 20141204; AU 2018200448 A1 20180215; CA 2872652 A1 20131114; EP 2866791 A1 20150506; EP 2866791 A4 20160420; HK 1211832 A1 20161014
DOCDB simple family (application)
US 2013039901 W 20130507; AU 2013259772 A 20130507; AU 2018200448 A 20180119; CA 2872652 A 20130507; EP 13788513 A 20130507; HK 15110912 A 20151105