EP 2872483 A1 20150520 - TRI-SALT FORM OF METFORMIN
Title (en)
TRI-SALT FORM OF METFORMIN
Title (de)
TRISALZFORM VON METFORMIN
Title (fr)
FORME À TROIS SELS DE METFORMINE
Publication
Application
Priority
- US 201261669763 P 20120710
- US 201261670368 P 20120711
- US 201261670376 P 20120711
- US 201313841970 A 20130315
- US 2013049984 W 20130710
Abstract (en)
[origin: WO2014011814A1] Provided herein are tri-salt compounds comprising a compound having two acidic functional groups and one basic functional groups (e.g., aspartate or glutamate), metformin, and polyunsaturated fatty acids, such as eicosapentaenoate or docosahexaenoate. The salts can be used in the treatment of diabetes, diabetes with concomitant dyslipidemia (e.g. , high triglycerides) and diabetes exacerbated cardiovascular complications, such as cardiac arrhythmia, cardiac ischemia, myocardial infarction, cardiomyopathy, and stroke. The compounds of this invention are also useful in treating obesity.
IPC 8 full level
C07C 279/26 (2006.01); A61K 31/155 (2006.01); A61K 31/205 (2006.01); A61P 3/10 (2006.01); A61P 9/04 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); C07C 229/24 (2006.01); C07C 277/08 (2006.01); C07C 279/02 (2006.01)
CPC (source: EP KR)
A61K 31/155 (2013.01 - EP KR); A61K 31/205 (2013.01 - KR); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/06 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 229/24 (2013.01 - EP KR); C07C 277/08 (2013.01 - EP KR); C07C 279/26 (2013.01 - EP KR)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014011814 A1 20140116; AU 2013290168 A1 20150205; BR 112015000368 A2 20170627; CA 2878819 A1 20140116; CN 104684889 A 20150603; EP 2872483 A1 20150520; EP 2872483 A4 20160316; IL 236613 A0 20150226; IN 76KON2015 A 20150731; JP 2015523382 A 20150813; KR 20150036235 A 20150407; MX 2015000408 A 20150714; ZA 201500274 B 20171025
DOCDB simple family (application)
US 2013049984 W 20130710; AU 2013290168 A 20130710; BR 112015000368 A 20130710; CA 2878819 A 20130710; CN 201380046842 A 20130710; EP 13817534 A 20130710; IL 23661315 A 20150111; IN 76KON2015 A 20150108; JP 2015521784 A 20130710; KR 20157002264 A 20130710; MX 2015000408 A 20130710; ZA 201500274 A 20150114