EP 2890682 A1 20150708 - PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES
Title (en)
PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES
Title (de)
VERFAHREN ZUR DECARBOXYLIERUNG VON 3,5-BIS(HALOALKYL)-PYRAZOL-4-CARBONSÄURE- DERIVATEN
Title (fr)
PROCÉDURE POUR LA DÉCARBOXYLATION DE DÉRIVÉS D'ACIDE 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIQUE
Publication
Application
Priority
- EP 12356019 A 20120830
- EP 2013067809 W 20130828
- EP 13758796 A 20130828
Abstract (en)
[origin: WO2014033164A1] A new process for the preparation of 3,5-bis(haloalkyl)-pyrazole derivatives of the general formula (I), is described, resulting from the reaction of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives of the general formula (IIa) with a copper compound and a base at elevated temperature wherein R1 is selected from H, C1-12-alkyl, C3-8-cycloalkyl, C6-18-aryl, C7-19-arylalkyl or C7-19-alkylaryl, CH2CN, CH2CX3, CH2COOH, CH2COO(C1-12)-alkyl, and X is independently of each other F, Cl, Br, I; R2 and R3 are selected independently of each other from C1-C6-haloalkyl.
IPC 8 full level
C07D 231/12 (2006.01); C07D 231/14 (2006.01)
CPC (source: BR CN EP US)
C07D 231/12 (2013.01 - BR CN EP US); C07D 231/14 (2013.01 - BR CN EP US)
Citation (search report)
See references of WO 2014033164A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014033164 A1 20140306; BR 112015004097 A2 20191022; BR 112015004097 B1 20200218; CN 104703972 A 20150610; CN 104703972 B 20170531; DK 2890682 T3 20160912; EP 2890682 A1 20150708; EP 2890682 B1 20160629; ES 2588386 T3 20161102; IL 237203 A0 20150430; IL 237203 A 20161130; JP 2015531342 A 20151102; JP 5931291 B2 20160608; KR 102140620 B1 20200803; KR 20150046292 A 20150429; MX 2015002419 A 20151106; MX 355542 B 20180420; TW 201422589 A 20140616; TW I609005 B 20171221; US 2015225350 A1 20150813; US 9145370 B2 20150929
DOCDB simple family (application)
EP 2013067809 W 20130828; BR 112015004097 A 20130828; CN 201380045648 A 20130828; DK 13758796 T 20130828; EP 13758796 A 20130828; ES 13758796 T 20130828; IL 23720315 A 20150212; JP 2015529002 A 20130828; KR 20157007647 A 20130828; MX 2015002419 A 20130828; TW 102130963 A 20130829; US 201314422891 A 20130828