EP 2895508 A1 20150722 - INHIBITORS OF BETA INTEGRIN-G PROTEIN ALPHA SUBUNIT BINDING INTERACTIONS
Title (en)
INHIBITORS OF BETA INTEGRIN-G PROTEIN ALPHA SUBUNIT BINDING INTERACTIONS
Title (de)
HEMMER VON INTERAKTIONEN, DIE BETA-INTEGRIN-G PROTEIN-ALPHA-UNTEREINHEIT BINDEN
Title (fr)
INHIBITEURS DES INTERACTIONS DE LIAISON DE LA SOUS-UNITÉ ALPHA DE PROTÉINE G-INTÉGRINE BÊTA
Publication
Application
Priority
- US 201213621064 A 20120915
- US 2013059833 W 20130913
Abstract (en)
[origin: CN104995207A] The invention relates inhibitors of beta integrin-g protein alpha subunit binding interactions. Provided herein are compounds that inhibit a binding interaction between a beta integrin and a G protein subunit, as well as compositions, e.g., pharmaceutical compositions, comprising the same, and related kits. In some embodiments, the compound is an antibody or antibody analog, and, in other embodiments, the compound is a peptide or peptide analog. Also provided are methods of using the compounds, including methods of treating or preventing a medical condition, such as stroke, heart attack, cancer, or inflammation.
IPC 8 full level
C07K 14/705 (2006.01)
CPC (source: EP)
C07K 14/70546 (2013.01); C07K 14/70557 (2013.01)
Citation (search report)
See references of WO 2014043594A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
CN 104995207 A 20151021; CN 104995207 B 20180807; EP 2895508 A1 20150722
DOCDB simple family (application)
CN 201380059929 A 20130913; EP 13783707 A 20130913