EP 2900662 A1 20150805 - A METHOD OF PREPARING A HIGHLY PURE POTASSIUM SALT OF AZILSARTAN MEDOXOMIL
Title (en)
A METHOD OF PREPARING A HIGHLY PURE POTASSIUM SALT OF AZILSARTAN MEDOXOMIL
Title (de)
VERFAHREN ZUR HERSTELLUNG EINES HOCHREINEN KALIUMSALZES AUS AZILSARTAN-MEDOXOMIL
Title (fr)
PROCÉDÉ DE PRÉPARATION D'UN SEL DE POTASSIUM D'AZILSARTAN MÉDOXOMIL HAUTEMENT PUR
Publication
Application
Priority
- CZ 2012663 A 20120926
- CZ 2013000114 W 20130925
Abstract (en)
[origin: WO2014048404A1] A method of preparing the potassium salt of azilsartan medoxomil of formula I, in which a solvate of azilsartan medoxomil of formula II with a solvent selected from the group that consists of dimethyl acetamide or N-methyl pyrrolidone or their mixtures with other solvents is prepared, or re-crystallized from dimethyl acetamide or N-methyl pyrrolidine or their mixtures with other solvents, and, in the next step, converted to the potassium salt using a potassium source in a suitable solvent.
IPC 8 full level
A61K 31/4245 (2006.01); A61P 9/12 (2006.01); C07D 413/14 (2006.01)
CPC (source: CN EP)
A61P 9/12 (2017.12 - EP); C07D 413/14 (2013.01 - CN EP)
Citation (search report)
See references of WO 2014048404A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014048404 A1 20140403; BR 112015006572 A2 20170704; CN 104662019 A 20150527; CZ 2012663 A3 20140402; CZ 305318 B6 20150729; EA 028171 B1 20171031; EA 201590657 A1 20150831; EP 2900662 A1 20150805; HK 1205505 A1 20151218; IL 237884 A0 20150531; JP 2015532267 A 20151109; KR 20150060733 A 20150603; MX 2015003209 A 20150714; UA 113668 C2 20170227
DOCDB simple family (application)
CZ 2013000114 W 20130925; BR 112015006572 A 20130925; CN 201380050044 A 20130925; CZ 2012663 A 20120926; EA 201590657 A 20130925; EP 13779507 A 20130925; HK 15106026 A 20150624; IL 23788415 A 20150322; JP 2015533448 A 20130925; KR 20157007800 A 20130925; MX 2015003209 A 20130925; UA A201503960 A 20130925