EP 2906248 B1 20181205 - PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
Title (en)
PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
Title (de)
PYRROLOBENZODIAZEPINE UND KONJUGATE DAVON
Title (fr)
PYRROLOBENZODIAZÉPINES ET LEURS CONJUGUÉS
Publication
Application
Priority
- US 201261712924 P 20121012
- EP 2013071235 W 20131011
Abstract (en)
[origin: WO2014057073A1] A compound which is selected from A, B and C, and salts and solvates thereof, as well as conjugates thereof with cell binding agents.
IPC 8 full level
A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61P 39/00 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01)
CPC (source: EP KR US)
A61K 47/68035 (2023.08 - EP KR US); A61K 47/6855 (2017.08 - EP KR US); A61P 35/00 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 39/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 403/12 (2013.01 - KR); C07D 487/04 (2013.01 - EP KR US); C07D 519/00 (2013.01 - EP US)
Citation (examination)
GREGSON S J ET AL: "Linker Length Modulates DNA Cross-Linking Reactivity and Cytotoxic Potency of C8/C8' Ether-Linked C2-exo-Unsaturated Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Dimers", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 47, 1 January 2004 (2004-01-01), pages 1161 - 1174, XP002316295, ISSN: 0022-2623, DOI: 10.1021/JM030897L
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2014057073 A1 20140417; AU 2013328674 A1 20150402; AU 2013328674 B2 20170622; BR 112015008251 A2 20170704; BR 112015008251 B1 20230926; CA 2885315 A1 20140417; CA 2885315 C 20200623; CA 3060520 A1 20140417; CA 3060520 C 20220517; CN 104703630 A 20150610; CN 110256469 A 20190920; CN 110256469 B 20220517; CY 1121390 T1 20200529; CY 1123778 T1 20220527; DK 2906248 T3 20190304; DK 3470086 T3 20201221; EP 2906248 A1 20150819; EP 2906248 B1 20181205; EP 3470086 A1 20190417; EP 3470086 B1 20201125; ES 2713164 T3 20190520; ES 2847050 T3 20210730; HK 1213183 A1 20160630; HR P20190366 T1 20190419; HR P20210126 T1 20210319; HU E043738 T2 20190930; HU E043738 T4 20200528; HU E052835 T2 20210528; JP 2015533141 A 20151119; JP 2018168182 A 20181101; JP 6367811 B2 20180801; JP 6516909 B2 20190522; KR 102138220 B1 20200727; KR 20150083994 A 20150721; KR 20190126197 A 20191108; KR 20200003278 A 20200108; LT 2906248 T 20190211; LT 3470086 T 20210225; MX 2015004560 A 20150721; MX 362004 B 20190103; MX 366303 B 20190704; NZ 705910 A 20180928; NZ 745069 A 20190531; PL 2906248 T3 20190531; PL 3470086 T3 20210531; PT 2906248 T 20190304; PT 3470086 T 20210201; RS 58203 B1 20190329; RS 61294 B1 20210226; SI 2906248 T1 20190228; SI 3470086 T1 20210331; TR 201902494 T4 20190321; US 2014120118 A1 20140501; US 9415117 B2 20160816; ZA 201501781 B 20160629
DOCDB simple family (application)
EP 2013071235 W 20131011; AU 2013328674 A 20131011; BR 112015008251 A 20131011; CA 2885315 A 20131011; CA 3060520 A 20131011; CN 201380053485 A 20131011; CN 201910645725 A 20131011; CY 191100233 T 20190226; CY 211100096 T 20210204; DK 13780099 T 20131011; DK 18187765 T 20131011; EP 13780099 A 20131011; EP 18187765 A 20131011; ES 13780099 T 20131011; ES 18187765 T 20131011; HK 16101149 A 20160201; HR P20190366 T 20190226; HR P20210126 T 20210122; HU E13780099 A 20131011; HU E18187765 A 20131011; JP 2015536139 A 20131011; JP 2018127804 A 20180704; KR 20157009875 A 20131011; KR 20197032333 A 20131011; KR 20197038868 A 20131011; LT 13780099 T 20131011; LT 18187765 T 20131011; MX 2015004560 A 20131011; MX 2018013577 A 20150410; NZ 70591013 A 20131011; NZ 74506913 A 20131011; PL 13780099 T 20131011; PL 18187765 T 20131011; PT 13780099 T 20131011; PT 18187765 T 20131011; RS P20190024 A 20131011; RS P20210002 A 20131011; SI 201331325 T 20131011; SI 201331845 T 20131011; TR 201902494 T 20131011; US 201314051717 A 20131011; ZA 201501781 A 20150316