EP 2906579 A1 20150819 - 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION
Title (en)
2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION
Title (de)
2'-CHLOR-NUKLEOSIDANALOGA FÜR HCV-INFEKTION
Title (fr)
ANALOGUES DE NUCLÉOSIDES 2'-CHLORO POUR TRAITER UNE INFECTION PAR LE VIRUS DE L'HÉPATITE C
Publication
Application
Priority
- US 201261711131 P 20121008
- US 201361807249 P 20130401
- US 2013063731 W 20131007
Abstract (en)
[origin: US2014099283A1] Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2′-chloro nucleosides according to Formula 2001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, Z and PD are as described herein.
IPC 8 full level
C07H 19/00 (2006.01); A61K 31/7068 (2006.01); A61K 31/7072 (2006.01); A61K 31/7076 (2006.01); A61K 31/708 (2006.01); A61P 31/04 (2006.01); C07H 19/06 (2006.01); C07H 19/16 (2006.01); C07H 19/20 (2006.01)
CPC (source: EP US)
A61K 31/403 (2013.01 - EP US); A61K 31/497 (2013.01 - EP US); A61K 31/706 (2013.01 - EP US); A61K 31/7064 (2013.01 - EP US); A61K 31/7068 (2013.01 - EP US); A61K 31/7072 (2013.01 - EP US); A61K 31/7076 (2013.01 - EP US); A61K 31/708 (2013.01 - EP US); A61K 31/7105 (2013.01 - EP US); A61K 38/212 (2013.01 - US); A61K 45/06 (2013.01 - EP US); A61P 1/16 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/14 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07H 19/06 (2013.01 - EP US); C07H 19/10 (2013.01 - EP US); C07H 19/11 (2013.01 - EP US); C07H 19/12 (2013.01 - US); C07H 19/14 (2013.01 - EP US); C07H 19/16 (2013.01 - EP US); C07H 19/20 (2013.01 - EP US); C07H 19/213 (2013.01 - EP US); C07H 19/23 (2013.01 - EP US)
Citation (search report)
See references of WO 2014058801A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
US 10513534 B2 20191224; US 2014099283 A1 20140410; AP 2015008384 A0 20150430; AU 2013329521 A1 20150528; AU 2013329521 B2 20180419; BR 112015007698 A2 20170822; CA 2887578 A1 20140417; CL 2015000870 A1 20151113; CN 104936970 A 20150923; CN 111848711 A 20201030; CR 20150199 A 20150901; DO P2015000079 A 20151130; EA 030189 B1 20180731; EA 030189 B8 20181031; EA 201500304 A1 20160129; EC SP15015737 A 20151231; EP 2906579 A1 20150819; EP 2906579 B1 20180418; ES 2674980 T3 20180705; GE P201706723 B 20170825; GT 201500086 A 20181219; HK 1207647 A1 20160205; IL 238088 A0 20150531; JP 2015535853 A 20151217; JP 6495822 B2 20190403; KR 102001280 B1 20190717; KR 20150084830 A 20150722; MD 20150036 A2 20150831; MX 2015004348 A 20151029; MX 353422 B 20180112; NI 201500049 A 20160216; NZ 706985 A 20180831; PE 20151318 A1 20151003; PH 12015500749 A1 20150525; SG 11201502750U A 20150629; TN 2015000117 A1 20160629; TR 201809048 T4 20180723; US 2016083413 A1 20160324; WO 2014058801 A1 20140417; ZA 201502545 B 20170830
DOCDB simple family (application)
US 201314047862 A 20131007; AP 2015008384 A 20131007; AU 2013329521 A 20131007; BR 112015007698 A 20131007; CA 2887578 A 20131007; CL 2015000870 A 20150407; CN 201380064162 A 20131007; CN 202010637082 A 20131007; CR 20150199 A 20150417; DO 2015000079 A 20150406; EA 201500304 A 20131007; EC PI201515737 A 20150421; EP 13776706 A 20131007; ES 13776706 T 20131007; GE AP2013013817 A 20131007; GT 201500086 A 20150407; HK 15108251 A 20150825; IL 23808815 A 20150401; JP 2015535875 A 20131007; KR 20157012119 A 20131007; MD 20150036 A 20131007; MX 2015004348 A 20131007; NI 201500049 A 20150407; NZ 70698513 A 20131007; PE 2015000459 A 20131007; PH 12015500749 A 20150406; SG 11201502750U A 20131007; TN 2015000117 A 20150326; TR 201809048 T 20131007; US 2013063731 W 20131007; US 201514920830 A 20151022; ZA 201502545 A 20150415