EP 2912512 A4 20160713 - QUANTITATIVE PHASE MICROSCOPY FOR LABEL-FREE HIGH-CONTRAST CELL IMAGING
Title (en)
QUANTITATIVE PHASE MICROSCOPY FOR LABEL-FREE HIGH-CONTRAST CELL IMAGING
Title (de)
QUANTITATIVE PHASENMIKROSKOPIE FÜR MARKIERUNGSFREIE ZELLENBILDGEBUNG MIT HOHEM KONTRAST
Title (fr)
MICROSCOPIE À PHASE QUANTITATIVE POUR L'IMAGERIE CELLULAIRE À CONTRASTE ÉLEVÉ SANS MARQUEUR
Publication
Application
Priority
- US 201213663069 A 20121029
- SE 2013051257 W 20131029
Abstract (en)
[origin: WO2014070082A1] Systems and methods described herein employ multiple phase-contrast images with various relative phase shifts between light diffracted by a sample and light not diffracted by the sample to produce a quantitative phase image. The produced quantitative phase image may have sufficient contrast for label-free auto-segmentation of cell bodies and nuclei.
IPC 8 full level
G02B 21/00 (2006.01); G02B 21/14 (2006.01)
CPC (source: EP)
G02B 21/0056 (2013.01); G02B 21/14 (2013.01)
Citation (search report)
- [I] WO 0125721 A1 20010412 - METROLASER INC [US], et al
- [A] WO 03002972 A2 20030109 - UNIV BRUXELLES [BE], et al
- [A] WO 2012103233 A1 20120802 - MASSACHUSETTS INST TECHNOLOGY [US], et al
- [A] US 2010231896 A1 20100916 - MANN CHRISTOPHER J [US], et al
- [A] US 2008285048 A1 20081120 - CHEN LIANG-CHIA [TW], et al
- [A] DUBOIS F ET AL: "Improved three-dimensional imaging with a digital holography microscope with a source of partial spatial coherence", APPLIED OPTICS, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC; US, vol. 38, no. 34, 1 December 1999 (1999-12-01), pages 7085 - 7094, XP002232391, ISSN: 0003-6935, DOI: 10.1364/AO.38.007085
- [A] ZHUO WANG ET AL: "Spatial light interference microscopy (SLIM)", OPTICS EXPRESS, vol. 19, no. 2, 17 January 2011 (2011-01-17), pages 1016, XP055145500, ISSN: 1094-4087, DOI: 10.1364/OE.19.001016
- See references of WO 2014070082A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2014070082 A1 20140508; EP 2912512 A1 20150902; EP 2912512 A4 20160713; JP 2015534134 A 20151126
DOCDB simple family (application)
SE 2013051257 W 20131029; EP 13851247 A 20131029; JP 2015539558 A 20131029