EP 2917225 A1 20150916 - PROCESS FOR MAKING ABIRATERONE-3-ACETATE
Title (en)
PROCESS FOR MAKING ABIRATERONE-3-ACETATE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ABIRATERON-3-ACETAT
Title (fr)
PROCÉDÉ DE FABRICATION DE 3-ACÉTATE D'ABIRATÉRONE
Publication
Application
Priority
EP 2012072208 W 20121109
Abstract (en)
[origin: WO2014071984A1] The present invention relates to an improved process for making abiraterone-3-acetate of formula (1) starting from dehydroepiandrosterone-3-acetate (DHEA) of formula (2). In particular, it relates to an improved process of converting the 17- triflate compound of formula (5) into abiraterone-3-acetate (1) in 2- methyl-THF as the solvent and producing a product of high purity via its acid addition salt abiraterone-3-acetate esylate (1A).
IPC 8 full level
C07J 31/00 (2006.01); C07J 43/00 (2006.01)
CPC (source: EP)
C07J 31/006 (2013.01); C07J 43/006 (2013.01)
Citation (search report)
See references of WO 2014071984A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014071984 A1 20140515; CA 2890589 A1 20140515; EP 2917225 A1 20150916
DOCDB simple family (application)
EP 2012072208 W 20121109; CA 2890589 A 20121109; EP 12784003 A 20121109