EP 2917226 A1 20150916 - PROCESS FOR MAKING THE 17-TRIFLATE INTERMEDIATE OF ABIRATERONE-3-ACETATE
Title (en)
PROCESS FOR MAKING THE 17-TRIFLATE INTERMEDIATE OF ABIRATERONE-3-ACETATE
Title (de)
VERFAHREN ZUR HERSTELLUNG DES 17-TRIFLAT-ZWISCHENPRODUKTS VON ABIRATERON-3-ACETAT
Title (fr)
PROCESSUS DE FABRICATION DE L'INTERMÉDIAIRE 17-TRIFLATE D'ABIRATÉRONE-3-ACÉTATE
Publication
Application
Priority
EP 2012072207 W 20121109
Abstract (en)
[origin: WO2014071983A1] The present invention relates to a process for making the compound 3β-acetoxy- androsta-5,16-dien-17-yl trifluoromethanesulfonate of formula (5) and is characterized in that dehydroepiandrosterone-3-acetate of formula (2) is reacted with a triflating agent, preferably trifluoromethanesulfonic anhydride, in an inert solvent in the absence of an organic base.
IPC 8 full level
C07J 43/00 (2006.01); C07J 75/00 (2006.01)
CPC (source: EP)
C07J 1/0011 (2013.01); C07J 31/006 (2013.01); C07J 43/003 (2013.01)
Citation (search report)
See references of WO 2014071983A1
Citation (examination)
WO 2014064032 A1 20140501 - OLON SPA [IT]
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2012072207 W 20121109; EP 12790830 A 20121109