EP 2922823 A4 20160504 - PYRIMIDINE PDE10 INHIBITORS
Title (en)
PYRIMIDINE PDE10 INHIBITORS
Title (de)
PDE10-PYRIMIDININHIBITOREN
Title (fr)
INHIBITEURS PYRIMIDINES DE PDE10
Publication
Application
Priority
- US 201261728464 P 20121120
- US 2013070214 W 20131115
Abstract (en)
[origin: WO2014081619A1] The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
IPC 8 full level
C07D 405/14 (2006.01); A61K 31/506 (2006.01); A61P 25/18 (2006.01); C07D 401/12 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP US)
A61P 25/18 (2017.12 - EP); C07D 401/12 (2013.01 - EP US); C07D 401/14 (2013.01 - EP US); C07D 405/14 (2013.01 - EP US); C07D 413/14 (2013.01 - EP US); C07D 417/14 (2013.01 - EP US); C07D 471/04 (2013.01 - EP US)
Citation (search report)
- [A] WO 2012044561 A2 20120405 - MERCK SHARP & DOHME [US], et al
- See references of WO 2014081619A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014081619 A1 20140530; EP 2922823 A1 20150930; EP 2922823 A4 20160504; EP 2922823 B1 20181031; US 2015307489 A1 20151029; US 9663513 B2 20170530
DOCDB simple family (application)
US 2013070214 W 20131115; EP 13856456 A 20131115; US 201314443619 A 20131115