EP 2931893 A1 20151021 - T-CELL MODULATION BY EXON SKIPPING
Title (en)
T-CELL MODULATION BY EXON SKIPPING
Title (de)
T-ZELLEN-MODULIERUNG DURCH EXON-SKIPPING
Title (fr)
MODULATION DES LYMPHOCYTES T PAR SAUT D'EXON
Publication
Application
Priority
- EP 12197023 A 20121213
- EP 2013076518 W 20131213
- EP 13803055 A 20131213
Abstract (en)
[origin: WO2014090985A1] The present application relates to a single stranded nucleic acid hybridizing to a splicing motif of an exon in a mRNA of a stimulating T-cell receptor or co-receptor, and wherein said exon codes for a transmembrane domain. Furthermore, the present application relates to methods of treating a transplant as well as to single stranded nucleic acids for use as a medicament, preferably for use in the treatment of graft versus host disease.
IPC 8 full level
C12N 15/113 (2010.01); A61K 31/712 (2006.01); A61P 37/06 (2006.01)
CPC (source: EP)
A61K 31/712 (2013.01); A61P 37/06 (2017.12); C12N 15/1138 (2013.01); C12N 2310/113 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/346 (2013.01); C12N 2320/33 (2013.01)
Citation (search report)
See references of WO 2014090985A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2013076518 W 20131213; EP 13803055 A 20131213