EP 2941441 A1 20151111 - METHOD FOR PRODUCING SECRETABLE ANTIBODIES BY EXPRESSION IN SACCHAROMYCES CEREVISIAE
Title (en)
METHOD FOR PRODUCING SECRETABLE ANTIBODIES BY EXPRESSION IN SACCHAROMYCES CEREVISIAE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON SEKRETIERBAREN ANTIKÖRPERN DURCH EXPRESSION IN SACCHAROMYCES CEREVISIAE
Title (fr)
PROCÉDÉ DE PRODUCTION D'ANTICORPS SÉCRÉTABLES PAR EXPRESSION DANS SACCHAROMYCES CEREVISIAE
Publication
Application
Priority
- EP 13000016 A 20130103
- EP 2013003748 W 20131211
- EP 13802890 A 20131211
Abstract (en)
[origin: WO2014106527A1] The invention relates to a method for the production and non-covalent surface display of antibodies and derived fragments as well as molecule libraries based thereon on the surface of S. cerevisiae cells. The non-covalent manner of the surface display enables specific variants to be selected by means of high-throughput screening and the selected binding molecule to be subsequently controllably secreted into the culture supernatant for biochemical characterization.
IPC 8 full level
C07K 16/00 (2006.01)
CPC (source: EP US)
C07K 16/005 (2013.01 - EP US); C12N 15/1037 (2013.01 - EP US); C07K 2317/14 (2013.01 - EP US); C07K 2317/569 (2013.01 - EP US); C07K 2317/624 (2013.01 - EP US)
Citation (search report)
See references of WO 2014106527A1
Citation (examination)
- "METHOCEL Cellulose Ethers - Technical Handbook", 2002, DOW, pages: cover, page 18, impressum
- "MAK- und BAT-Werte", 1995, WILEY-VCH, article POLYETHYLENGLYKOLE, MAK, LIEFERUNG 21, 1995
- ED HARLOW, DAVID LANE: "Antibodies - A Laboratory Manual", 1988, COLDSPRING HARBOR LABORATORIES, pages: cover, page 201, impressum
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014106527 A1 20140710; AU 2013372026 A1 20150813; AU 2013372026 B2 20181108; CA 2896908 A1 20140710; CN 104870471 A 20150826; EP 2941441 A1 20151111; IL 239689 A0 20150831; JP 2016501913 A 20160121; JP 6421944 B2 20181114; US 10138477 B2 20181127; US 2015337292 A1 20151126
DOCDB simple family (application)
EP 2013003748 W 20131211; AU 2013372026 A 20131211; CA 2896908 A 20131211; CN 201380069362 A 20131211; EP 13802890 A 20131211; IL 23968915 A 20150629; JP 2015551138 A 20131211; US 201314758856 A 20131211