EP 2955185 A1 20151216 - POLYCYCLIC SUBSTITUTED PYRAZOLE KINASE ACTIVITY INHIBITORS AND USE THEREOF
Title (en)
POLYCYCLIC SUBSTITUTED PYRAZOLE KINASE ACTIVITY INHIBITORS AND USE THEREOF
Title (de)
POLYCYCLISCHE SUBSTITUIERTE PYRAZOLKINASEAKTIVITÄTSHEMMER UND VERWENDUNG DAVON
Title (fr)
INHIBITEURS DE L'ACTIVITÉ DE LA PYRAZOLE KINASE POLYCYCLIQUE SUBSTITUÉE ET LEUR UTILISATION
Publication
Application
Priority
- CN 201310005258 A 20130108
- CN 2014070195 W 20140107
Abstract (en)
The present invention relates to the field of medicinal chemistry, and in particular relates to 4-(five-membered heterocyclic pyrimidine/pyridine substituted) amino-1H-3-pyrazolecarboxamide derivatives, the preparation method thereof, pharmaceutical compositions containing these compounds and the medicinal use thereof, especially as protein kinase inhibitors for anti-tumour use.
IPC 8 full level
C07D 495/04 (2006.01); A01N 43/64 (2006.01); A01N 43/72 (2006.01); A61K 31/496 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 493/04 (2006.01)
CPC (source: CN EP RU US)
A01N 43/90 (2013.01 - RU); A61K 31/496 (2013.01 - RU); A61K 31/519 (2013.01 - RU); A61K 31/5377 (2013.01 - RU); A61P 3/10 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 17/02 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 25/02 (2018.01 - EP); A61P 25/08 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/10 (2018.01 - EP); A61P 31/12 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/02 (2018.01 - EP); A61P 37/06 (2018.01 - EP); C07D 471/04 (2013.01 - CN EP RU US); C07D 487/04 (2013.01 - CN EP RU US); C07D 491/048 (2013.01 - CN EP RU US); C07D 493/04 (2013.01 - EP US); C07D 495/04 (2013.01 - CN EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 2955185 A1 20151216; EP 2955185 A4 20160608; EP 2955185 B1 20210106; AU 2014204633 A1 20150827; AU 2014204633 B2 20170727; BR 112015016327 A2 20170711; BR 112015016327 A8 20180123; CA 2897366 A1 20140717; CA 2897366 C 20210105; CN 103012428 A 20130403; CN 105189517 A 20151223; CN 105189517 B 20170718; CN 107098903 A 20170829; CN 107098903 B 20200717; DK 2955185 T3 20210329; ES 2863175 T3 20211008; JP 2016504395 A 20160212; JP 6322848 B2 20180516; KR 102136628 B1 20200723; KR 20150120966 A 20151028; PT 2955185 T 20210223; RU 2015133528 A 20170215; RU 2655921 C2 20180530; US 2015368259 A1 20151224; US 9550792 B2 20170124; WO 2014108053 A1 20140717
DOCDB simple family (application)
EP 14738057 A 20140107; AU 2014204633 A 20140107; BR 112015016327 A 20140107; CA 2897366 A 20140107; CN 201310005258 A 20130108; CN 2014070195 W 20140107; CN 201480004085 A 20140107; CN 201710450213 A 20140107; DK 14738057 T 20140107; ES 14738057 T 20140107; JP 2015551972 A 20140107; KR 20157021621 A 20140107; PT 14738057 T 20140107; RU 2015133528 A 20140107; US 201414759516 A 20140107