EP 2968340 A1 20160120 - COMBINATION OF A PI3K INHIBITOR AND AN MTOR INHIBITOR
Title (en)
COMBINATION OF A PI3K INHIBITOR AND AN MTOR INHIBITOR
Title (de)
KOMBINATION VON EINEM PI3K HEMMER UND EINEM MTOR-HEMMER
Title (fr)
COMBINAISON D'UN INHIBITEURS PI3K ET D'UN INHIBITEUR MTOR
Publication
Application
Priority
- US 201313843816 A 20130315
- US 201314099644 A 20131206
- US 2014025090 W 20140312
Abstract (en)
[origin: WO2014151147A1] The present invention provides for a method for treating a disease condition associated with PI3-kinase a and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase a and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth. The present invention also provides a pharmaceutical kit effective for treating a disease condition associated with PI3 -kinase α and/or mTOR in a subject.
IPC 8 full level
A61K 31/437 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 31/337 (2013.01); A61K 31/423 (2013.01); A61K 31/436 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/4745 (2013.01); A61K 31/497 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 13/12 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 37/06 (2017.12); A61P 43/00 (2017.12)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014151147 A1 20140925; CA 2906542 A1 20140925; CN 105246482 A 20160113; EP 2968340 A1 20160120; EP 2968340 A4 20160810; HK 1219421 A1 20170407; JP 2016512835 A 20160509
DOCDB simple family (application)
US 2014025090 W 20140312; CA 2906542 A 20140312; CN 201480026545 A 20140312; EP 14771022 A 20140312; HK 16107451 A 20160627; JP 2016501741 A 20140312