EP 2968340 A4 20160810 - COMBINATION OF KINASE INHIBITORS AND USES THEREOF
Title (en)
COMBINATION OF KINASE INHIBITORS AND USES THEREOF
Title (de)
KOMBINATION VON KINASEINHIBITOREN UND VERWENDUNGEN DAVON
Title (fr)
COMBINAISON D'INHIBITEURS DE KINASE ET SES UTILISATIONS
Publication
Application
Priority
- US 201313843816 A 20130315
- US 201314099644 A 20131206
- US 2014025090 W 20140312
Abstract (en)
[origin: WO2014151147A1] The present invention provides for a method for treating a disease condition associated with PI3-kinase a and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase a and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth. The present invention also provides a pharmaceutical kit effective for treating a disease condition associated with PI3 -kinase α and/or mTOR in a subject.
IPC 8 full level
A61K 31/519 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 31/337 (2013.01); A61K 31/423 (2013.01); A61K 31/436 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/4745 (2013.01); A61K 31/497 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 13/12 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 37/06 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
- [X] WO 2008124026 A1 20081016 - WYETH CORP [US], et al
- [X] WO 2012068106 A2 20120524 - EXELIXIS INC [US], et al
- [E] WO 2014046617 A1 20140327 - AGENCY SCIENCE TECH & RES [SG]
- [A] WO 2010006072 A2 20100114 - UNIV CALIFORNIA [US], et al
- [T] ANONYMOUS: "mTOR inhibitors - Wikipedia, the free encyclopedia", 22 June 2016 (2016-06-22), XP055286199, Retrieved from the Internet <URL:https://en.wikipedia.org/wiki/MTOR_inhibitors> [retrieved on 20160706]
- See references of WO 2014151147A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014151147 A1 20140925; CA 2906542 A1 20140925; CN 105246482 A 20160113; EP 2968340 A1 20160120; EP 2968340 A4 20160810; HK 1219421 A1 20170407; JP 2016512835 A 20160509
DOCDB simple family (application)
US 2014025090 W 20140312; CA 2906542 A 20140312; CN 201480026545 A 20140312; EP 14771022 A 20140312; HK 16107451 A 20160627; JP 2016501741 A 20140312