EP 2972374 A2 20160120 - RATIO BASED BIOMARKERS AND METHODS OF USE THEREOF
Title (en)
RATIO BASED BIOMARKERS AND METHODS OF USE THEREOF
Title (de)
VERHÄLTNISBASIERTE BASIERENDE BIOMARKER UND VERFAHREN ZUR VERWENDUNG DAVON
Title (fr)
BIOMARQUEURS BASÉS SUR LE RAPPORT ET LEUR PROCÉDÉS D'UTILISATION
Publication
Application
Priority
- US 201313841176 A 20130315
- US 2014024936 W 20140312
Abstract (en)
[origin: WO2014151079A2] Compositions, methods and kits are described for identifying biomolecules (e.g., proteins and nucleic acids) expressed in a biological sample that are associated with the presence, development, or progression of a disease (such as cancer), or more generally determination of the etiology or risk factors associated with a disease. Sample types analyzed by the disclosed methods include but are not limited to archival tissue blocks that have been preserved in a fixative, tissue biopsy samples, tissue microarrays, and so forth. The methods disclosed herein correlate expression profiles of biomolecules with various disease types, and allow for the determination of relative survival rates; in some embodiments, the methods permit determination of survival rates for a subject with cancer. In other embodiments, the disclosure relates to methods for evaluating therapeutic regimes for the treatment, such as treatment of cancer.
IPC 8 full level
G01N 33/574 (2006.01)
CPC (source: EP)
G01N 33/574 (2013.01); G01N 33/57411 (2013.01)
Citation (search report)
See references of WO 2014151079A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014151079 A2 20140925; WO 2014151079 A3 20150305; WO 2014151079 A8 20150430; CA 2904973 A1 20140925; EP 2972374 A2 20160120
DOCDB simple family (application)
US 2014024936 W 20140312; CA 2904973 A 20140312; EP 14723537 A 20140312