EP 2975942 B1 20180808 - TARGETED DISRUPTION OF T CELL RECEPTOR GENES USING ENGINEERED ZINC FINGER PROTEIN NUCLEASES
Title (en)
TARGETED DISRUPTION OF T CELL RECEPTOR GENES USING ENGINEERED ZINC FINGER PROTEIN NUCLEASES
Title (de)
GEZIELTE DISRUPTION VON T-ZELL REZEPTORGENEN MIT MANIPULIERTEN ZINKFINGER-PROTEINNUKLEASEN
Title (fr)
INTERRUPTION CIBLÉE DE GÈNES DE RÉCEPTEUR DES LYMPHOCYTES T À L'AIDE DE NUCLÉASES PROTÉIQUES À DOIGT DE ZINC GÉNÉTIQUEMENT MODIFIÉES
Publication
Application
Priority
- US 201361804076 P 20130321
- US 2014031360 W 20140320
Abstract (en)
[origin: WO2014153470A2] Disclosed herein are methods and compositions for modifying TCR genes, using nucleases (zinc finger nucleases or TAL nucleases) to modify TCR genes.
IPC 8 full level
A01N 63/00 (2006.01); C07H 21/04 (2006.01); C12N 9/16 (2006.01); C12N 15/00 (2006.01)
CPC (source: EP IL US)
A61K 35/26 (2013.01 - EP IL US); A61K 39/0011 (2013.01 - US); A61K 39/001188 (2018.08 - US); A61K 39/4611 (2023.05 - EP IL); A61K 39/4632 (2023.05 - EP IL); A61K 39/464453 (2023.05 - EP IL); A61K 39/464488 (2023.05 - EP IL); A61P 31/00 (2018.01 - EP IL); A61P 35/00 (2018.01 - EP IL); A61P 37/06 (2018.01 - EP IL); C12N 15/86 (2013.01 - EP IL US); C12N 15/87 (2013.01 - EP IL US); C12N 15/907 (2013.01 - EP IL US); A61K 2039/5156 (2013.01 - US); A61K 2039/5158 (2013.01 - US); A61K 2239/38 (2023.05 - EP IL); A61K 2239/48 (2023.05 - EP IL); C12N 2501/515 (2013.01 - EP IL US); C12N 2510/00 (2013.01 - EP IL US); C12N 2740/16043 (2013.01 - EP IL US)
Citation (examination)
- WO 2013074916 A1 20130523 - UNIV TEXAS [US]
- WO 2012012667 A2 20120126 - SANGAMO BIOSCIENCES INC [US], et al & DATABASE Geneseq [online] 15 March 2012 (2012-03-15), "Human TRAC gene target site, SEQ ID 128.", retrieved from EBI accession no. GSN:AZS87188 Database accession no. AZS87188 & DATABASE Geneseq [online] 15 March 2012 (2012-03-15), "Human TRAC gene target site, SEQ ID 129.", retrieved from EBI accession no. GSN:AZS87189 Database accession no. AZS87189 & DATABASE Geneseq [online] 15 March 2012 (2012-03-15), "Human TRBC gene target site, SEQ ID 130.", retrieved from EBI accession no. GSN:AZS87190 Database accession no. AZS87190 & DATABASE Geneseq [online] 15 March 2012 (2012-03-15), "Human TRBC gene target site, SEQ ID 131.", retrieved from EBI accession no. GSN:AZS87191 Database accession no. AZS87191
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2014153470 A2 20140925; WO 2014153470 A3 20141204; AU 2014235968 A1 20151001; AU 2014235968 B2 20180524; CA 2906970 A1 20140925; CA 2906970 C 20210518; CN 105208866 A 20151230; CN 105208866 B 20181123; EP 2975942 A2 20160127; EP 2975942 A4 20161109; EP 2975942 B1 20180808; HK 1218232 A1 20170210; IL 241583 B 20210531; JP 2016515822 A 20160602; JP 6346266 B2 20180620; US 10918668 B2 20210216; US 2014301990 A1 20141009; US 2018214485 A1 20180802; US 9937207 B2 20180410
DOCDB simple family (application)
US 2014031360 W 20140320; AU 2014235968 A 20140320; CA 2906970 A 20140320; CN 201480020893 A 20140320; EP 14770870 A 20140320; HK 16106201 A 20160531; IL 24158315 A 20150910; JP 2016504364 A 20140320; US 201414221074 A 20140320; US 201815936210 A 20180326