EP 2989099 A1 20160302 - A PROCESS FOR THE SYNTHESIS OF MARAVIROC
Title (en)
A PROCESS FOR THE SYNTHESIS OF MARAVIROC
Title (de)
VERFAHREN ZUR SYNTHESE VON MARAVIROC
Title (fr)
PROCÉDÉ DE SYNTHÈSE DE MARAVIROC
Publication
Application
Priority
- CZ 2013315 A 20130426
- CZ 2014000038 W 20140418
Abstract (en)
[origin: WO2014173375A1] A process for the synthesis of Maraviroc The invention relates to a new approach to synthesis of Maraviroc, a substance with the chemical name N-{(lS)-3-[3-(3-isopropy)-5- methyl-4 H-l,2,4-triazol-4-yl-exo-8-azabicyclo-[3.2.1]oct-8-yl]-l- phenylpropyl}-4,4-difluorocyclohexanecarboxamide and the structure of formula I using the "borrowing hydrogen" method also called "hydrogen autotransfer" method as well as improved isolation and purification of the final product.
IPC 8 full level
C07D 451/02 (2006.01)
CPC (source: EP)
C07D 451/02 (2013.01)
Citation (search report)
See references of WO 2014173375A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014173375 A1 20141030; WO 2014173375 A8 20150108; CZ 2013315 A3 20141105; CZ 306455 B6 20170201; EP 2989099 A1 20160302
DOCDB simple family (application)
CZ 2014000038 W 20140418; CZ 2013315 A 20130426; EP 14723973 A 20140418