EP 2994224 A1 20160316 - AQUEOUS FORMULATIONS OF SPARINGLY WATER-SOLUBLE ACTIVE INGREDIENTS COMPRISING AS SOLUBILIZER A MIXTURE OF POLOXAMERS DIFFERING IN HYDROPHOBICITY
Title (en)
AQUEOUS FORMULATIONS OF SPARINGLY WATER-SOLUBLE ACTIVE INGREDIENTS COMPRISING AS SOLUBILIZER A MIXTURE OF POLOXAMERS DIFFERING IN HYDROPHOBICITY
Title (de)
WÄSSRIGE FORMULIERUNGEN VON IN WASSER SCHWERLÖSLICHEN WIRKSTOFFEN ENTHALTEND ALS SOLUBILISATOR EINE MISCHUNG AUS POLOXAMEREN MIT UNTERSCHIEDLICHER HYDROPHOBIZITÄT
Title (fr)
FORMULATIONS AQUEUSES DE SUBSTANCES ACTIVES DIFFICILEMENT SOLUBLES DANS L'EAU CONTENANT COMME SOLUBILISANT, UN MÉLANGE DE POLOXAMÈRES PRÉSENTANT DES HYDROPHOBIES DIFFÉRENTES
Publication
Application
Priority
- EP 13166662 A 20130506
- EP 2014058435 W 20140425
- EP 14719746 A 20140425
Abstract (en)
[origin: WO2014180677A1] The use of a mixture a) of a hydroxy-terminated polyether of the block structure (A) (EO)x1'–(PO)y1 –(EO)x1'', where y1 is 40 to 70 and (x1'+x1'') is 30 –60 and (x1' + x1'') / y1 is less than 1 (component A), and b) of a hydroxy-terminated polyether of the block structure (B) (EO)x2'–(PO)y2 –(EO)x2'', where y2 is 15 to 55 and ( x2' + x2'') is 2 –50 and (x2' + x2'') / y2 is less than 1 (component B), with (x1' + x1'') / y1 > (x2' + x2'') / y2, for solubilizing sparingly water-soluble active ingredients, having a water-solubility at 25 °C and 0.1013 MPa of not more than 5 g/l, in aqueous formulations.
IPC 8 full level
C09K 23/42 (2022.01); A01N 25/30 (2006.01); A01N 43/56 (2006.01); A61K 47/10 (2006.01)
CPC (source: EP US)
A01N 25/02 (2013.01 - US); A01N 25/30 (2013.01 - EP US); A01N 43/56 (2013.01 - US); A61K 8/90 (2013.01 - EP US); A61K 9/08 (2013.01 - EP US); A61K 31/216 (2013.01 - EP US); A61K 31/415 (2013.01 - EP US); A61K 47/10 (2013.01 - EP US); A61K 47/34 (2013.01 - US); A61Q 19/00 (2013.01 - EP US); C09K 23/42 (2022.01 - EP US); A61K 2800/10 (2013.01 - EP US); A61K 2800/49 (2013.01 - EP US)
Citation (search report)
See references of WO 2014180677A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2014180677 A1 20141113; BR 112015027112 A2 20170725; CN 105188901 A 20151223; EP 2994224 A1 20160316; JP 2016520422 A 20160714; US 2016074517 A1 20160317
DOCDB simple family (application)
EP 2014058435 W 20140425; BR 112015027112 A 20140425; CN 201480025422 A 20140425; EP 14719746 A 20140425; JP 2016512275 A 20140425; US 201414888951 A 20140425