EP 3010906 B1 20190612 - BENZIMIDAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS
Title (en)
BENZIMIDAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS
Title (de)
BENZIMIDAZOLDERIVATE ALS SELEKTIVE PROTEINKINASEINHIBITOREN
Title (fr)
DÉRIVÉS DE BENZIMIDAZOLE EN TANT QU'INHIBITEURS SÉLECTIFS DE PROTÉINE KINASE
Publication
Application
Priority
- EP 13305837 A 20130620
- EP 2014063045 W 20140620
- EP 14732550 A 20140620
Abstract (en)
[origin: WO2014202763A1] The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof. Wherein n, R1, R2, R3, R4, R5, A, Q and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.
IPC 8 full level
C07D 401/14 (2006.01); A61K 31/427 (2006.01); A61K 31/4406 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61P 17/00 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP US)
A61K 8/49 (2013.01 - EP US); A61K 31/427 (2013.01 - EP US); A61K 31/4439 (2013.01 - EP US); A61K 31/506 (2013.01 - EP US); A61K 31/5377 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 17/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61Q 19/00 (2013.01 - EP US); C07D 401/14 (2013.01 - EP US); C07D 413/14 (2013.01 - EP US); C07D 417/12 (2013.01 - EP US); C07D 417/14 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2014202763 A1 20141224; AR 096654 A1 20160127; EP 3010906 A1 20160427; EP 3010906 B1 20190612; HK 1222396 A1 20170630; TW 201534597 A 20150916; US 10202370 B2 20190212; US 2016152608 A1 20160602
DOCDB simple family (application)
EP 2014063045 W 20140620; AR P140102316 A 20140619; EP 14732550 A 20140620; HK 16110610 A 20160906; TW 103121276 A 20140619; US 201414900008 A 20140620