EP 3019870 B1 20180418 - METHOD FOR THE QUANTITATIVE CHARACTERISATION OF AMYLOID AND/OR AGGREGATING PEPTIDES AND/OR PROTEINS IN A SAMPLE
Title (en)
METHOD FOR THE QUANTITATIVE CHARACTERISATION OF AMYLOID AND/OR AGGREGATING PEPTIDES AND/OR PROTEINS IN A SAMPLE
Title (de)
VERFAHREN ZUR QUANTITATIVEN CHARAKTERISIERUNG AMYLOIDER UND/ODER AGGREGIERENDER PEPTIDE UND/ODER PROTEINE IN EINER PROBE
Title (fr)
PROCÉDÉ DE CARACTÉRISATION QUANTITATIVE DE PEPTIDES ET/OU DE PROTÉINES AMYLOÏDES ET/OU AGRÉGÉS DANS UN ÉCHANTILLON
Publication
Application
Priority
- DE 102013011634 A 20130712
- DE 2014000319 W 20140625
Abstract (en)
[origin: WO2015003674A2] The invention relates to a method for the quantitative characterisation of amyloid and/or aggregated peptides and/or proteins in a sample, comprising the following steps: preparing a sample containing an amyloid and/or aggregated peptide and/or protein having at least one aggregate size and shape; adding an active ingredient to be analysed to the sample solution; separating the amyloid and/or aggregated peptides and/or proteins from one another according to their aggregate size and shape; optionally completely denaturing the amyloid and/or aggregated peptides and/or proteins of a particular fraction into monomer units; comparing against control values without the active ingredient in order to determine the change in concentration of the peptide and/or protein units in at least one fraction.
IPC 8 full level
G01N 33/68 (2006.01); B01D 15/32 (2006.01)
CPC (source: EP US)
B01D 15/325 (2013.01 - EP US); G01N 30/89 (2013.01 - US); G01N 33/6845 (2013.01 - EP US); G01N 33/6896 (2013.01 - US); G01N 2333/4709 (2013.01 - US); G01N 2500/00 (2013.01 - EP US); G01N 2500/20 (2013.01 - US); G01N 2800/2821 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2015003674 A2 20150115; WO 2015003674 A3 20150903; DE 102013011634 A1 20150129; DK 3019870 T3 20180625; EP 3019870 A2 20160518; EP 3019870 B1 20180418; ES 2670545 T3 20180530; US 10088487 B2 20181002; US 2016349273 A1 20161201
DOCDB simple family (application)
DE 2014000319 W 20140625; DE 102013011634 A 20130712; DK 14761560 T 20140625; EP 14761560 A 20140625; ES 14761560 T 20140625; US 201414902754 A 20140625