EP 3046556 A4 20170426 - COMBINATION DRUG THERAPY
Title (en)
COMBINATION DRUG THERAPY
Title (de)
KOMBINATIONSWIRKSTOFFTHERAPIE
Title (fr)
POLYTHÉRAPIE MÉDICAMENTEUSE
Publication
Application
Priority
- US 201361879895 P 20130919
- US 2014055816 W 20140916
Abstract (en)
[origin: WO2015042029A1] A novel combination comprising the androgen receptor inhibitor, 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide or a pharmaceutically acceptable salt or solvate thereof, with a PI3Kß inhibitor, 2-methyl-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of using such combinations and compositions in the treatment of conditions in which the inhibition of androgen receptor and/or PI3Kß is beneficial, e.g., cancer.
IPC 8 full level
A61K 31/4166 (2006.01); A61K 31/535 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 35/04 (2006.01); C07D 233/86 (2006.01); C07D 413/10 (2006.01)
CPC (source: EP US)
A61K 31/4166 (2013.01 - EP US); A61K 31/535 (2013.01 - EP US); A61K 31/5377 (2013.01 - US); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
- [AP] WO 2014108837 A1 20140717 - GLAXOSMITHKLINE IP NO 2 LTD [GB]
- [AP] WO 2014113260 A1 20140724 - ARAGON PHARMACEUTICALS INC [US]
- See references of WO 2015042029A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015042029 A1 20150326; AU 2014321456 A1 20160310; AU 2014321456 B2 20180524; BR 112016005000 A8 20180123; CA 2921156 A1 20150326; CN 105530934 A 20160427; EP 3046556 A1 20160727; EP 3046556 A4 20170426; JP 2016530208 A 20160929; JP 2018158930 A 20181011; JP 2019196391 A 20191114; JP 6346944 B2 20180620; JP 6563558 B2 20190821; KR 20160055911 A 20160518; RU 2016110546 A 20171024; RU 2016110546 A3 20180320; US 2016228446 A1 20160811
DOCDB simple family (application)
US 2014055816 W 20140916; AU 2014321456 A 20140916; BR 112016005000 A 20140916; CA 2921156 A 20140916; CN 201480051583 A 20140916; EP 14846138 A 20140916; JP 2016515414 A 20140916; JP 2018101120 A 20180528; JP 2019135772 A 20190724; KR 20167009965 A 20140916; RU 2016110546 A 20140916; US 201415022561 A 20140916