EP 3046912 A1 20160727 - DISUBSTITUTED TRIFLUORMETHYLPYRIMIDINONES AND USE THEREOF AS CCR2 ANTAGONISTS
Title (en)
DISUBSTITUTED TRIFLUORMETHYLPYRIMIDINONES AND USE THEREOF AS CCR2 ANTAGONISTS
Title (de)
DISUBSTITUIERTE TRIFLUORMETHYLPYRIMIDINONE UND IHRE VERWENDUNG ALS CCR2 ANTAGONISTEN
Title (fr)
TRIFLUORMETHYLPYRIMIDINONES DISUBSTITUÉES ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE CCR2
Publication
Application
Priority
- EP 13184481 A 20130916
- EP 2014069540 W 20140912
- EP 14766967 A 20140912
Abstract (en)
[origin: WO2015036563A1] The invention relates to novel 2,5-disubstituted-6-(trifluoromethyl)pyrimidine-4(3H-one derivates, to a method for the production thereof, to the use thereof either alone or in combination for the treatment and/or prevention of diseases, and to the use thereof for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular, renal, inflammatory and fibrotic diseases.
IPC 8 full level
A61K 31/513 (2006.01); A61P 9/00 (2006.01); A61P 29/00 (2006.01); C07D 239/36 (2006.01); C07D 239/47 (2006.01); C07D 239/54 (2006.01); C07D 239/545 (2006.01); C07D 239/56 (2006.01)
CPC (source: EP US)
A61K 31/513 (2013.01 - US); A61K 45/06 (2013.01 - US); A61P 9/00 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 29/00 (2017.12 - EP); C07D 239/36 (2013.01 - EP US); C07D 239/47 (2013.01 - EP US); C07D 239/52 (2013.01 - EP US); C07D 239/54 (2013.01 - EP US); C07D 239/545 (2013.01 - EP US); C07D 239/56 (2013.01 - EP US); C07D 401/06 (2013.01 - EP US); C07D 401/12 (2013.01 - EP US)
Citation (search report)
See references of WO 2015036563A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015036563 A1 20150319; AR 097665 A1 20160406; EP 3046912 A1 20160727; TW 201605812 A 20160216; US 2016221965 A1 20160804; UY 35735 A 20150430
DOCDB simple family (application)
EP 2014069540 W 20140912; AR P140103432 A 20140915; EP 14766967 A 20140912; TW 103131480 A 20140912; US 201415021372 A 20140912; UY 35735 A 20140912